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YTHDC2 | YTH domain containing 2 (1430 aa) | |||
MCM5 | minichromosome maintenance complex component 5; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ’once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute dif [...] (734 aa) | |||
BYSL | bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos (437 aa) | |||
HEMK1 | HemK methyltransferase family member 1; N5-glutamine methyltransferase responsible for the methylation of the GGQ triplet of the mitochondrial translation release factor MTRF1L (338 aa) | |||
FAM86B2 | family with sequence similarity 86, member B2 (330 aa) | |||
DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8; Facilitates nuclear export of spliced mRNA by releasing the RNA from the spliceosome (1220 aa) | |||
ANKRD10 | ankyrin repeat domain 10 (420 aa) | |||
GFM2 | G elongation factor, mitochondrial 2; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation (779 aa) | |||
RRM1 | ribonucleotide reductase M1; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) (792 aa) | |||
N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative); Heterodimeric methyltransferase that catalyzes N5- methylation of ETF1 on ’Gln-185’, using S-adenosyl L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid (214 aa) | |||
DHX37 | DEAH (Asp-Glu-Ala-His) box polypeptide 37 (1157 aa) | |||
RIPK4 | receptor-interacting serine-threonine kinase 4; Involved in stratified epithelial development. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation (784 aa) | |||
DHX15 | DEAH (Asp-Glu-Ala-His) box polypeptide 15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA (By similarity) (795 aa) | |||
FAM86C1 | family with sequence similarity 86, member C1 (165 aa) | |||
ANKRD16 | ankyrin repeat domain 16 (361 aa) | |||
FAM50B | family with sequence similarity 50, member B (325 aa) | |||
CWC27 | CWC27 spliceosome-associated protein homolog (S. cerevisiae); PPIases accelerate the folding of proteins (By similarity) (472 aa) | |||
ALKBH8 | alkB, alkylation repair homolog 8 (E. coli); Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis (664 aa) | |||
ANKRD39 | ankyrin repeat domain 39 (183 aa) | |||
FAM50A | family with sequence similarity 50, member A; May be a DNA-binding protein or transcriptional factor (339 aa) | |||
CTU1 | cytosolic thiouridylase subunit 1 homolog (S. pombe); Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position (348 aa) | |||
FAM86A | family with sequence similarity 86, member A (330 aa) | |||
FAM86B1 | family with sequence similarity 86, member B1 (330 aa) | |||
TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae); Participates both in methylation of protein and tRNA species. The heterodimer with HEMK2/N6AMT1 catalyzes N5- methylation of ETF1 on ’Gln-185’, using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species (125 aa) | |||
RPS15 | ribosomal protein S15 (145 aa) | |||
ENSG00000268412 | Uncharacterized protein (135 aa) |