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  • 10.0 (archived version)
STRINGSTRING
RPL6 RPL6 CD151 CD151 PTGFRN PTGFRN CD82 CD82 CD9 CD9 CD81 CD81 TRIB1 TRIB1 CD63 CD63
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
CD9CD9 molecule; Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion (228 aa)
RPL6ribosomal protein L6; Specifically binds to domain C of the Tax-responsive enhancer element in the long terminal repeat of HTLV-I (288 aa)
CD82CD82 molecule; Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway (267 aa)
CD63CD63 molecule; This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation (238 aa)
CD81CD81 molecule; May play an important role in the regulation of lymphoma cell growth. Interacts with a 16-kDa Leu-13 protein to form a complex possibly involved in signal transduction. May act as the viral receptor for HCV (236 aa)
TRIB1tribbles homolog 1 (Drosophila); Interacts with MAPK kinases and regulates activation of MAP kinases. May not display kinase activity (372 aa)
CD151CD151 molecule (Raph blood group); Essential for the proper assembly of the glomerular and tubular basement membranes in kidney (253 aa)
PTGFRNprostaglandin F2 receptor negative regulator; Inhibits the binding of prostaglandin F2-alpha (PGF2- alpha) to its specific FP receptor, by decreasing the receptor number rather than the affinity constant. Functional coupling with the prostaglandin F2-alpha receptor seems to occur (By similarity) (879 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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