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RAD54L2 RAD54L2 ATRX ATRX CHD2 CHD2 FHL3 FHL3 SLC35A2 SLC35A2 SLC35A3 SLC35A3 PRICKLE1 PRICKLE1 MYO5A MYO5A SLC35F5 SLC35F5 SLC35A1 SLC35A1 PRICKLE2 PRICKLE2 TMCC1 TMCC1 RAP1B RAP1B SHPRH SHPRH ZDHHC17 ZDHHC17 CHD1 CHD1 SLC35A4 SLC35A4 CHD6 CHD6 CHD9 CHD9 SLC35A5 SLC35A5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
SLC35F5solute carrier family 35, member F5; Putative solute transporter (Potential) (523 aa)
SLC35A2solute carrier family 35 (UDP-galactose transporter), member A2; Transports nucleotide sugars from the cytosol into Golgi vesicles where glycosyltransferases function (396 aa)
RAP1BRAP1B, member of RAS oncogene family (184 aa)
SHPRHSNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase (1683 aa)
CHD1chromodomain helicase DNA binding protein 1; ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome. Is also associated wit [...] (1710 aa)
PRICKLE2prickle homolog 2 (Drosophila) (844 aa)
SLC35A4solute carrier family 35, member A4 (324 aa)
PRICKLE1prickle homolog 1 (Drosophila); Involved in the planar cell polarity pathway that controls convergent extension during gastrulation and neural tube closure. Convergent extension is a complex morphogenetic process during which cells elongate, move mediolaterally, and intercalate between neighboring cells, leading to convergence toward the mediolateral axis and extension along the anteroposterior axis. Necessary for nuclear localization of REST. May serve as nuclear receptor (831 aa)
SLC35A1solute carrier family 35 (CMP-sialic acid transporter), member A1; Transports CMP-sialic acid from the cytosol into Golgi vesicles where glycosyltransferases function (337 aa)
SLC35A3solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3; Uridine diphosphate-N-acetylglucosamine transporter in the Golgi apparatus (325 aa)
FHL3four and a half LIM domains 3 (280 aa)
CHD6chromodomain helicase DNA binding protein 6 (2715 aa)
ATRXalpha thalassemia/mental retardation syndrome X-linked (2492 aa)
TMCC1transmembrane and coiled-coil domain family 1 (653 aa)
CHD2chromodomain helicase DNA binding protein 2; Sequence-selective DNA-binding protein (By similarity) (1828 aa)
MYO5Amyosin VA (heavy chain 12, myoxin); Processive actin-based motor that can move in large steps approximating the 36-nm pseudo-repeat of the actin filament. Involved in melanosome transport. Also mediates the transport of vesicles to the plasma membrane. May also be required for some polarization process involved in dendrite formation (1855 aa)
RAD54L2RAD54-like 2 (S. cerevisiae); DNA helicase that modulates androgen receptor (AR)- dependent transactivation in a promoter-dependent manner. Not able to remodel mononucleosomes in vitro (By similarity) (1467 aa)
ZDHHC17zinc finger, DHHC-type containing 17; Palmitoyltransferase specific for a subset of neuronal proteins, including SNAP25, DLG4/PSD95, GAD2, SYT1 and HD. Palmitoylates MPP1 in erythrocytes. May be involved in the sorting or targeting of critical proteins involved in the initiating events of endocytosis at the plasma membrane. Has transforming activity. Mediates Mg(2+) transport (632 aa)
SLC35A5solute carrier family 35, member A5 (424 aa)
CHD9chromodomain helicase DNA binding protein 9; Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis (By similarity) (2881 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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