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CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain (296 aa) | |||
CD82 | CD82 molecule; Associates with CD4 or CD8 and delivers costimulatory signals for the TCR/CD3 pathway (267 aa) | |||
HSPA8 | heat shock 70kDa protein 8; Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19- CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex (646 aa) | |||
CD63 | CD63 molecule; This antigen is associated with early stages of melanoma tumor progression. May play a role in growth regulation (238 aa) | |||
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide (255 aa) | |||
ANXA11 | annexin A11; Binds specifically to calcyclin in a calcium-dependent manner (By similarity). Required for midbody formation and completion of the terminal phase of cytokinesis (505 aa) | |||
MARCH1 | membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination of TFRC, CD86, FAS and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. By constitutively ubiquitinating MHC class II proteins in immature dendritic cells, down-regulates their cell surface localization thus sequestering them in the intracellular endosomal system (289 aa) | |||
MS4A1 | membrane-spanning 4-domains, subfamily A, member 1; This protein may be involved in the regulation of B-cell activation and proliferation (297 aa) | |||
PKM | pyruvate kinase, muscle (531 aa) | |||
HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (724 aa) | |||
HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function (854 aa) | |||
UBC | ubiquitin C (685 aa) | |||
HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 (266 aa) | |||
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane (303 aa) | |||
HLA-DMA | major histocompatibility complex, class II, DM alpha (261 aa) | |||
HLA-DRB5 | major histocompatibility complex, class II, DR beta 5 (266 aa) | |||
HLA-C | major histocompatibility complex, class I, C; Involved in the presentation of foreign antigens to the immune system (By similarity) (366 aa) | |||
PRPF40B | PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae); May be involved in pre-mRNA splicing (871 aa) | |||
MBP | myelin basic protein (197 aa) | |||
HLA-DRA | major histocompatibility complex, class II, DR alpha (254 aa) | |||
HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 (261 aa) | |||
HLA-DOB | major histocompatibility complex, class II, DO beta (273 aa) | |||
HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 (227 aa) | |||
HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 (258 aa) |