node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCC2 | CHCHD2 | ENSP00000359478 | ENSP00000378812 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter | coiled-coil-helix-coiled-coil-helix domain containing 2 | 0.644 |
ABCC2 | UBC | ENSP00000359478 | ENSP00000344818 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter | ubiquitin C | 0.861 |
CHCHD2 | ABCC2 | ENSP00000378812 | ENSP00000359478 | coiled-coil-helix-coiled-coil-helix domain containing 2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter | 0.644 |
CHCHD2 | COX5B | ENSP00000378812 | ENSP00000258424 | coiled-coil-helix-coiled-coil-helix domain containing 2 | cytochrome c oxidase subunit Vb; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport | 0.689 |
CHCHD2 | DSG2 | ENSP00000378812 | ENSP00000261590 | coiled-coil-helix-coiled-coil-helix domain containing 2 | desmoglein 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion | 0.644 |
CHCHD2 | HTT | ENSP00000378812 | ENSP00000347184 | coiled-coil-helix-coiled-coil-helix domain containing 2 | huntingtin; May play a role in microtubule-mediated transport or vesicle function | 0.412 |
CHCHD2 | RPL24 | ENSP00000378812 | ENSP00000377640 | coiled-coil-helix-coiled-coil-helix domain containing 2 | ribosomal protein L24 | 0.644 |
CHCHD2 | UBC | ENSP00000378812 | ENSP00000344818 | coiled-coil-helix-coiled-coil-helix domain containing 2 | ubiquitin C | 0.507 |
COX5B | CHCHD2 | ENSP00000258424 | ENSP00000378812 | cytochrome c oxidase subunit Vb; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport | coiled-coil-helix-coiled-coil-helix domain containing 2 | 0.689 |
COX5B | UBC | ENSP00000258424 | ENSP00000344818 | cytochrome c oxidase subunit Vb; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport | ubiquitin C | 0.801 |
DSG2 | CHCHD2 | ENSP00000261590 | ENSP00000378812 | desmoglein 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion | coiled-coil-helix-coiled-coil-helix domain containing 2 | 0.644 |
DSG2 | UBC | ENSP00000261590 | ENSP00000344818 | desmoglein 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion | ubiquitin C | 0.893 |
EHMT2 | SIRT1 | ENSP00000364687 | ENSP00000212015 | euchromatic histone-lysine N-methyltransferase 2 | sirtuin 1; NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression. Deacetylates a broad range of transcription factors and coregulators, thereby regulating target gene expression positively and negatively. Se [...] | 0.611 |
EHMT2 | UBC | ENSP00000364687 | ENSP00000344818 | euchromatic histone-lysine N-methyltransferase 2 | ubiquitin C | 0.835 |
HTT | CHCHD2 | ENSP00000347184 | ENSP00000378812 | huntingtin; May play a role in microtubule-mediated transport or vesicle function | coiled-coil-helix-coiled-coil-helix domain containing 2 | 0.412 |
HTT | UBC | ENSP00000347184 | ENSP00000344818 | huntingtin; May play a role in microtubule-mediated transport or vesicle function | ubiquitin C | 0.999 |
RPL24 | CHCHD2 | ENSP00000377640 | ENSP00000378812 | ribosomal protein L24 | coiled-coil-helix-coiled-coil-helix domain containing 2 | 0.644 |
RPL24 | UBC | ENSP00000377640 | ENSP00000344818 | ribosomal protein L24 | ubiquitin C | 0.997 |
SIRT1 | EHMT2 | ENSP00000212015 | ENSP00000364687 | sirtuin 1; NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression. Deacetylates a broad range of transcription factors and coregulators, thereby regulating target gene expression positively and negatively. Se [...] | euchromatic histone-lysine N-methyltransferase 2 | 0.611 |
SIRT1 | UBC | ENSP00000212015 | ENSP00000344818 | sirtuin 1; NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metobolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression. Deacetylates a broad range of transcription factors and coregulators, thereby regulating target gene expression positively and negatively. Se [...] | ubiquitin C | 0.963 |