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SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2; Low-affinity, high capacity permease involved in the transport of the cationic amino acids (arginine, lysine and ornithine). Plays a regulatory role in classical or alternative activation of macrophages (By similarity) (698 aa) | |||
EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase (723 aa) | |||
SLC7A10 | solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10; Sodium-independent, high affinity transport of small neutral D- and L-amino acids. May play a role in the modulation of glutamatergic transmission through mobilization of D-serine at the glutamatergic synapse (523 aa) | |||
NDUFS3 | NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase); Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) (264 aa) | |||
SLC12A7 | solute carrier family 12 (potassium/chloride transporters), member 7; Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters’ cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification (By similarity) (1083 aa) | |||
SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp); Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor (664 aa) | |||
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate (501 aa) | |||
SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7; Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L- arginine in monocytes (511 aa) | |||
SLC7A13 | solute carrier family 7 (anionic amino acid transporter), member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner (By similarity) (470 aa) | |||
SLC7A3 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 3; Mediates the uptake of the cationic amino acids arginine, lysine and ornithine in a sodium-independent manner (619 aa) | |||
CRYL1 | crystallin, lambda 1 (319 aa) | |||
SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8; Sodium-independent, high-affinity transport of small and large neutral amino acids such as alanine, serine, threonine, cysteine, phenylalanine, tyrosine, leucine, arginine and tryptophan, when associated with SLC3A2/4F2hc. Acts as an amino acid exchanger. Has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. Plays a role in basolateral (re)absorption of neutral amino acids. Involved in the uptake of methylme [...] (535 aa) | |||
MT-ND5 | mitochondrially encoded NADH dehydrogenase 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) (603 aa) | |||
MT-ND4 | mitochondrially encoded NADH dehydrogenase 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) (459 aa) | |||
MT-ND2 | mitochondrially encoded NADH dehydrogenase 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) (347 aa) | |||
MT-ND3 | mitochondrially encoded NADH dehydrogenase 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) (115 aa) | |||
ECI2 | enoyl-CoA delta isomerase 2 (394 aa) | |||
HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit (763 aa) | |||
SLC12A1 | solute carrier family 12 (sodium/potassium/chloride transporters), member 1; Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume (1099 aa) | |||
SLC12A8 | solute carrier family 12 (potassium/chloride transporters), member 8 (714 aa) | |||
SLC5A12 | solute carrier family 5 (sodium/glucose cotransporter), member 12; Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D- hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina (By similarity). Mediates electroneutral [...] (618 aa) | |||
HADH | hydroxyacyl-CoA dehydrogenase; Plays an essential role in the mitochondrial beta- oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA (331 aa) | |||
SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5; Mediates electroneutral potassium-chloride cotransport in mature neurons. Transport occurs under isotonic conditions, but is activated 20-fold by cell swelling. Important for Cl(-) homeostasis in neurons (1139 aa) | |||
SLC12A3 | solute carrier family 12 (sodium/chloride transporters), member 3; Key mediator of sodium and chloride reabsorption in this nephron segment, accounting for a significant fraction of renal sodium reabsorption (1030 aa) | |||
SLC12A6 | solute carrier family 12 (potassium/chloride transporters), member 6 (1141 aa) | |||
ENSG00000268864 | Uncharacterized protein (142 aa) |