node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APOA1 | APOA2 | ENSP00000236850 | ENSP00000356969 | apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | 0.997 |
APOA1 | APOB | ENSP00000236850 | ENSP00000233242 | apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility | apolipoprotein B (including Ag(x) antigen) | 0.999 |
APOA1 | APOF | ENSP00000236850 | ENSP00000381250 | apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility | apolipoprotein F; Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII | 0.791 |
APOA1 | CETP | ENSP00000236850 | ENSP00000200676 | apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility | cholesteryl ester transfer protein, plasma; Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol | 0.987 |
APOA2 | APOA1 | ENSP00000356969 | ENSP00000236850 | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility | 0.997 |
APOA2 | APOB | ENSP00000356969 | ENSP00000233242 | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | apolipoprotein B (including Ag(x) antigen) | 0.993 |
APOA2 | APOF | ENSP00000356969 | ENSP00000381250 | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | apolipoprotein F; Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII | 0.746 |
APOA2 | CETP | ENSP00000356969 | ENSP00000200676 | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | cholesteryl ester transfer protein, plasma; Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol | 0.563 |
APOB | APOA1 | ENSP00000233242 | ENSP00000236850 | apolipoprotein B (including Ag(x) antigen) | apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility | 0.999 |
APOB | APOA2 | ENSP00000233242 | ENSP00000356969 | apolipoprotein B (including Ag(x) antigen) | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | 0.993 |
APOB | APOF | ENSP00000233242 | ENSP00000381250 | apolipoprotein B (including Ag(x) antigen) | apolipoprotein F; Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII | 0.942 |
APOB | CETP | ENSP00000233242 | ENSP00000200676 | apolipoprotein B (including Ag(x) antigen) | cholesteryl ester transfer protein, plasma; Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol | 0.975 |
APOF | APOA1 | ENSP00000381250 | ENSP00000236850 | apolipoprotein F; Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII | apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility | 0.791 |
APOF | APOA2 | ENSP00000381250 | ENSP00000356969 | apolipoprotein F; Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | 0.746 |
APOF | APOB | ENSP00000381250 | ENSP00000233242 | apolipoprotein F; Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII | apolipoprotein B (including Ag(x) antigen) | 0.942 |
APOF | CETP | ENSP00000381250 | ENSP00000200676 | apolipoprotein F; Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII | cholesteryl ester transfer protein, plasma; Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol | 0.980 |
CETP | APOA1 | ENSP00000200676 | ENSP00000236850 | cholesteryl ester transfer protein, plasma; Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol | apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility | 0.987 |
CETP | APOA2 | ENSP00000200676 | ENSP00000356969 | cholesteryl ester transfer protein, plasma; Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | 0.563 |
CETP | APOB | ENSP00000200676 | ENSP00000233242 | cholesteryl ester transfer protein, plasma; Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol | apolipoprotein B (including Ag(x) antigen) | 0.975 |
CETP | APOF | ENSP00000200676 | ENSP00000381250 | cholesteryl ester transfer protein, plasma; Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol | apolipoprotein F; Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII | 0.980 |