node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COL12A1 | COL13A1 | ENSP00000325146 | ENSP00000381949 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XIII, alpha 1 | 0.918 |
COL12A1 | COL15A1 | ENSP00000325146 | ENSP00000364140 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle | 0.940 |
COL12A1 | COL16A1 | ENSP00000325146 | ENSP00000362776 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XVI, alpha 1; Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology | 0.915 |
COL12A1 | COL17A1 | ENSP00000325146 | ENSP00000340937 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XVII, alpha 1; May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane | 0.921 |
COL12A1 | COL18A1 | ENSP00000325146 | ENSP00000347665 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XVIII, alpha 1 | 0.933 |
COL12A1 | COL19A1 | ENSP00000325146 | ENSP00000316030 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XIX, alpha 1 | 0.929 |
COL12A1 | COL20A1 | ENSP00000325146 | ENSP00000351767 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XX, alpha 1; Probable collagen protein | 0.904 |
COL12A1 | COL23A1 | ENSP00000325146 | ENSP00000375069 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XXIII, alpha 1 | 0.910 |
COL12A1 | COL24A1 | ENSP00000325146 | ENSP00000359603 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XXIV, alpha 1; May participate in regulating type I collagen fibrillogenesis at specific anatomical locations during fetal development | 0.931 |
COL12A1 | COL25A1 | ENSP00000325146 | ENSP00000382083 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XXV, alpha 1; Inhibits fibrillization of beta amyloid peptide during the elongation phase. Has also been shown to assemble amyloid fibrils into protease-resistant aggregates. Binds heparin | 0.917 |
COL12A1 | COL27A1 | ENSP00000325146 | ENSP00000348385 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XXVII, alpha 1; Plays a role during the calcification of cartilage and the transition of cartilage to bone | 0.906 |
COL12A1 | COL28A1 | ENSP00000325146 | ENSP00000382356 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XXVIII, alpha 1; May act as a cell-binding protein | 0.900 |
COL12A1 | COL2A1 | ENSP00000325146 | ENSP00000369889 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type II, alpha 1 | 0.918 |
COL12A1 | COL3A1 | ENSP00000325146 | ENSP00000304408 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type III, alpha 1 | 0.948 |
COL12A1 | COL4A2 | ENSP00000325146 | ENSP00000353654 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type IV, alpha 2; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | 0.935 |
COL12A1 | COL4A3 | ENSP00000325146 | ENSP00000379823 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.901 |
COL12A1 | COL4A4 | ENSP00000325146 | ENSP00000379866 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type IV, alpha 4; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | 0.900 |
COL12A1 | COL5A1 | ENSP00000325146 | ENSP00000360882 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type V, alpha 1; Type V collagen is a member of group I collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V collagen binds to DNA, heparan sulfate, thrombospondin, heparin, and insulin | 0.952 |
COL12A1 | COL5A2 | ENSP00000325146 | ENSP00000364000 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type V, alpha 2 | 0.944 |
COL12A1 | COL6A1 | ENSP00000325146 | ENSP00000355180 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type VI, alpha 1; Collagen VI acts as a cell-binding protein | 0.926 |