6 items (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	EHD4	EH-domain containing 4; Plays a role in early endosomal transport (541 aa)
	EHD2	EH-domain containing 2; Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP (By similarity) (543 aa)
	EHD1	EH-domain containing 1; Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes (534 aa)
	EHD3	EH-domain containing 3; Plays a role in endocytic transport (535 aa)
	UBC	ubiquitin C (685 aa)
	FER1L6	fer-1-like 6 (C. elegans) (1857 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EHD1	EHD2	ENSP00000320516	ENSP00000263277	EH-domain containing 1; Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes	EH-domain containing 2; Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP (By similarity)	0.907
EHD1	EHD3	ENSP00000320516	ENSP00000327116	EH-domain containing 1; Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes	EH-domain containing 3; Plays a role in endocytic transport	0.956
EHD1	EHD4	ENSP00000320516	ENSP00000220325	EH-domain containing 1; Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes	EH-domain containing 4; Plays a role in early endosomal transport	0.999
EHD1	FER1L6	ENSP00000320516	ENSP00000381982	EH-domain containing 1; Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes	fer-1-like 6 (C. elegans)	0.413
EHD1	UBC	ENSP00000320516	ENSP00000344818	EH-domain containing 1; Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes	ubiquitin C	0.812
EHD2	EHD1	ENSP00000263277	ENSP00000320516	EH-domain containing 2; Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP (By similarity)	EH-domain containing 1; Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes	0.907
EHD2	EHD3	ENSP00000263277	ENSP00000327116	EH-domain containing 2; Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP (By similarity)	EH-domain containing 3; Plays a role in endocytic transport	0.912
EHD2	FER1L6	ENSP00000263277	ENSP00000381982	EH-domain containing 2; Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP (By similarity)	fer-1-like 6 (C. elegans)	0.494
EHD2	UBC	ENSP00000263277	ENSP00000344818	EH-domain containing 2; Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP (By similarity)	ubiquitin C	0.652
EHD3	EHD1	ENSP00000327116	ENSP00000320516	EH-domain containing 3; Plays a role in endocytic transport	EH-domain containing 1; Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes	0.956
EHD3	EHD2	ENSP00000327116	ENSP00000263277	EH-domain containing 3; Plays a role in endocytic transport	EH-domain containing 2; Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP (By similarity)	0.912
EHD3	FER1L6	ENSP00000327116	ENSP00000381982	EH-domain containing 3; Plays a role in endocytic transport	fer-1-like 6 (C. elegans)	0.447
EHD3	UBC	ENSP00000327116	ENSP00000344818	EH-domain containing 3; Plays a role in endocytic transport	ubiquitin C	0.528
EHD4	EHD1	ENSP00000220325	ENSP00000320516	EH-domain containing 4; Plays a role in early endosomal transport	EH-domain containing 1; Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes	0.999
EHD4	UBC	ENSP00000220325	ENSP00000344818	EH-domain containing 4; Plays a role in early endosomal transport	ubiquitin C	0.896
FER1L6	EHD1	ENSP00000381982	ENSP00000320516	fer-1-like 6 (C. elegans)	EH-domain containing 1; Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes	0.413
FER1L6	EHD2	ENSP00000381982	ENSP00000263277	fer-1-like 6 (C. elegans)	EH-domain containing 2; Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP (By similarity)	0.494
FER1L6	EHD3	ENSP00000381982	ENSP00000327116	fer-1-like 6 (C. elegans)	EH-domain containing 3; Plays a role in endocytic transport	0.447
UBC	EHD1	ENSP00000344818	ENSP00000320516	ubiquitin C	EH-domain containing 1; Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes	0.812
UBC	EHD2	ENSP00000344818	ENSP00000263277	ubiquitin C	EH-domain containing 2; Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP (By similarity)	0.652

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