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GTPBP1 | GTP binding protein 1; Promotes degradation of target mRNA species. Plays a role in the regulation of circadian mRNA stability. Binds GTP and has GTPase activity (By similarity) (669 aa) | |||
PDIA2 | protein disulfide isomerase family A, member 2; Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins (525 aa) | |||
SOGA1 | suppressor of glucose, autophagy associated 1; Regulates autophagy by playing a role in the reduction of glucose production in an adiponectin- and insulin-dependent manner (By similarity) (1661 aa) | |||
ACTN4 | actinin, alpha 4; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (911 aa) | |||
MIB1 | mindbomb E3 ubiquitin protein ligase 1 (1006 aa) | |||
NDUFB10 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (172 aa) | |||
PDIA4 | protein disulfide isomerase family A, member 4 (645 aa) | |||
MYO1E | myosin IE; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain. Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by con [...] (1108 aa) | |||
FYCO1 | FYVE and coiled-coil domain containing 1; May mediate microtubule plus end-directed vesicle transport (1478 aa) | |||
PDIA3 | protein disulfide isomerase family A, member 3 (505 aa) | |||
GTPBP2 | GTP binding protein 2 (602 aa) | |||
SEC24C | SEC24 family, member C (S. cerevisiae); Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex (1094 aa) | |||
P4HB | prolyl 4-hydroxylase, beta polypeptide; This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell, seems to form/rearrange disulfide bonds of nascent proteins. At high concentrations, functions as a chaperone that inhibits aggregation of misfolded proteins. At low concentrations, facilitates aggregation (anti-chaperone activity). May be involved with [...] (508 aa) | |||
SOGA2 | SOGA family member 2 (1586 aa) | |||
DMD | dystrophin (3685 aa) | |||
ACTN2 | actinin, alpha 2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (894 aa) | |||
UTRN | utrophin; May play a role in anchoring the cytoskeleton to the plasma membrane (By similarity) (3433 aa) | |||
SOGA3 | SOGA family member 3 (947 aa) | |||
DLG5 | discs, large homolog 5 (Drosophila) (1919 aa) | |||
SAR1A | SAR1 homolog A (S. cerevisiae); Involved in transport from the endoplasmic reticulum to the Golgi apparatus (By similarity). Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (198 aa) | |||
SQSTM1 | sequestosome 1; Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures). Links ALIS to the autophagic machinery via direct interaction with MAP1 LC3 family members. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, ap [...] (440 aa) | |||
ACTN1 | actinin, alpha 1; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein (914 aa) | |||
SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1); Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (538 aa) | |||
DTNA | dystrobrevin, alpha (743 aa) | |||
MIB2 | mindbomb E3 ubiquitin protein ligase 2 (1070 aa) | |||
C6orf174 | C6orf174 protein (947 aa) |