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SLC22A23 SLC22A23 LGALS8 LGALS8 PLA2G4A PLA2G4A ABCG4 ABCG4 ADTRP ADTRP ABCG1 ABCG1 ORMDL3 ORMDL3 SLC2A6 SLC2A6 ABCG5 ABCG5 SLC2A10 SLC2A10 ABCG8 ABCG8 SLC2A12 SLC2A12 ARHGDIA ARHGDIA ESYT3 ESYT3 ARHGDIG ARHGDIG ARHGDIB ARHGDIB SLC2A8 SLC2A8 SLC2A13 SLC2A13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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ARHGDIGRho GDP dissociation inhibitor (GDI) gamma; Inhibits GDP/GTP exchange reaction of RhoB. Interacts specifically with the GDP- and GTP-bound forms of post- translationally processed Rhob and Rhog proteins, both of which show a growth-regulated expression in mammalian cells. Stimulates the release of the GDP-bound but not the GTP-bound RhoB protein. Also inhibits the GDP/GTP exchange of RhoB but shows less ability to inhibit the dissociation of prebound GTP (225 aa)
ARHGDIBRho GDP dissociation inhibitor (GDI) beta; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them (201 aa)
ADTRPandrogen-dependent TFPI-regulating protein; Regulates the expression and the cell-associated anticoagulant activity of the inhibitor TFPI in endothelial cells (in vitro) (248 aa)
ABCG5ATP-binding cassette, sub-family G (WHITE), member 5; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (651 aa)
ARHGDIARho GDP dissociation inhibitor (GDI) alpha; Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1 (By similarity) (204 aa)
ABCG8ATP-binding cassette, sub-family G (WHITE), member 8; Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (673 aa)
SLC2A12solute carrier family 2 (facilitated glucose transporter), member 12; Facilitative glucose transporter (By similarity) (617 aa)
SLC2A13solute carrier family 2 (facilitated glucose transporter), member 13; H(+)-myo-inositol cotransporter. Can also transport related stereoisomers (648 aa)
ABCG4ATP-binding cassette, sub-family G (WHITE), member 4; May be involved in macrophage lipid homeostasis (646 aa)
ORMDL3ORM1-like 3 (S. cerevisiae); Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling (153 aa)
LGALS8lectin, galactoside-binding, soluble, 8 (359 aa)
SLC2A10solute carrier family 2 (facilitated glucose transporter), member 10; Facilitative glucose transporter (541 aa)
ABCG1ATP-binding cassette, sub-family G (WHITE), member 1 (678 aa)
PLA2G4Aphospholipase A2, group IVA (cytosolic, calcium-dependent); Selectively hydrolyzes arachidonyl phospholipids in the sn-2 position releasing arachidonic acid. Together with its lysophospholipid activity, it is implicated in the initiation of the inflammatory response (749 aa)
SLC2A6solute carrier family 2 (facilitated glucose transporter), member 6; Facilitative glucose transporter; binds cytochalasin B with low affinity (507 aa)
SLC2A8solute carrier family 2 (facilitated glucose transporter), member 8; Insulin-regulated facilitative glucose transporter. Binds cytochalasin B in a glucose-inhibitable manner. Seems to be a dual-specific sugar transporter as it is inhibitable by fructose (By similarity) (477 aa)
ESYT3extended synaptotagmin-like protein 3; May play a role as calcium-regulated intrinsic membrane protein (By similarity) (886 aa)
SLC22A23solute carrier family 22, member 23 (686 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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