9 items (Homo sapiens) - STRING network view

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Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

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Your Input:
	STX6	syntaxin 6; Involved in intracellular vesicle trafficking (255 aa)
	SDCBP	syndecan binding protein (syntenin); Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway (298 aa)
	VPS54	vacuolar protein sorting 54 homolog (S. cerevisiae); May be involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (977 aa)
	STX8	syntaxin 8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER (236 aa)
	UBC	ubiquitin C (685 aa)
	BAI3	brain-specific angiogenesis inhibitor 3; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Might be involved in angiogenesis inhibition and suppression of glioblastoma (1522 aa)
	CCDC75	coiled-coil domain containing 75 (259 aa)
	VPS52	vacuolar protein sorting 52 homolog (S. cerevisiae); May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD (723 aa)
	STX10	syntaxin 10; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network (249 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BAI3	CCDC75	ENSP00000359630	ENSP00000386772	brain-specific angiogenesis inhibitor 3; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Might be involved in angiogenesis inhibition and suppression of glioblastoma	coiled-coil domain containing 75	0.612
CCDC75	BAI3	ENSP00000386772	ENSP00000359630	coiled-coil domain containing 75	brain-specific angiogenesis inhibitor 3; May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses. Might be involved in angiogenesis inhibition and suppression of glioblastoma	0.612
CCDC75	UBC	ENSP00000386772	ENSP00000344818	coiled-coil domain containing 75	ubiquitin C	0.620
CCDC75	VPS54	ENSP00000386772	ENSP00000272322	coiled-coil domain containing 75	vacuolar protein sorting 54 homolog (S. cerevisiae); May be involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD	0.455
SDCBP	UBC	ENSP00000260130	ENSP00000344818	syndecan binding protein (syntenin); Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway	ubiquitin C	0.969
STX10	STX6	ENSP00000466298	ENSP00000258301	syntaxin 10; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network	syntaxin 6; Involved in intracellular vesicle trafficking	0.551
STX10	STX8	ENSP00000466298	ENSP00000305255	syntaxin 10; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network	syntaxin 8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER	0.800
STX10	UBC	ENSP00000466298	ENSP00000344818	syntaxin 10; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network	ubiquitin C	0.567
STX10	VPS52	ENSP00000466298	ENSP00000409952	syntaxin 10; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network	vacuolar protein sorting 52 homolog (S. cerevisiae); May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD	0.689
STX10	VPS54	ENSP00000466298	ENSP00000272322	syntaxin 10; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network	vacuolar protein sorting 54 homolog (S. cerevisiae); May be involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD	0.639
STX6	STX10	ENSP00000258301	ENSP00000466298	syntaxin 6; Involved in intracellular vesicle trafficking	syntaxin 10; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network	0.551
STX6	STX8	ENSP00000258301	ENSP00000305255	syntaxin 6; Involved in intracellular vesicle trafficking	syntaxin 8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER	0.833
STX6	UBC	ENSP00000258301	ENSP00000344818	syntaxin 6; Involved in intracellular vesicle trafficking	ubiquitin C	0.907
STX6	VPS52	ENSP00000258301	ENSP00000409952	syntaxin 6; Involved in intracellular vesicle trafficking	vacuolar protein sorting 52 homolog (S. cerevisiae); May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD	0.838
STX6	VPS54	ENSP00000258301	ENSP00000272322	syntaxin 6; Involved in intracellular vesicle trafficking	vacuolar protein sorting 54 homolog (S. cerevisiae); May be involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD	0.838
STX8	STX10	ENSP00000305255	ENSP00000466298	syntaxin 8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER	syntaxin 10; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network	0.800
STX8	STX6	ENSP00000305255	ENSP00000258301	syntaxin 8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER	syntaxin 6; Involved in intracellular vesicle trafficking	0.833
STX8	UBC	ENSP00000305255	ENSP00000344818	syntaxin 8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER	ubiquitin C	0.917
STX8	VPS52	ENSP00000305255	ENSP00000409952	syntaxin 8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER	vacuolar protein sorting 52 homolog (S. cerevisiae); May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD	0.558
STX8	VPS54	ENSP00000305255	ENSP00000272322	syntaxin 8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER	vacuolar protein sorting 54 homolog (S. cerevisiae); May be involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD	0.545

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