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ENO2 | enolase 2 (gamma, neuronal); Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity) (434 aa) | |||
ENO1 | enolase 1, (alpha) (434 aa) | |||
MPHOSPH10 | M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (681 aa) | |||
UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae); Essential for gene silencing- has a role in the structure of silenced chromatin. Plays a role in the developing brain (By similarity) (479 aa) | |||
TREH | trehalase (brush-border membrane glycoprotein); Intestinal trehalase is probably involved in the hydrolysis of ingested trehalose (582 aa) | |||
QARS | glutaminyl-tRNA synthetase (775 aa) | |||
SLC37A2 | solute carrier family 37 (glycerol-3-phosphate transporter), member 2 (505 aa) | |||
DIS3L2 | DIS3 mitotic control homolog (S. cerevisiae)-like 2; Ribonuclease that plays a critical role in RNA metabolism. It is essential for correct mitosis, and negatively regulates cell proliferation (885 aa) | |||
SLC37A3 | solute carrier family 37 (glycerol-3-phosphate transporter), member 3 (494 aa) | |||
DIS3L | DIS3 mitotic control homolog (S. cerevisiae)-like; Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3’ untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA (1054 aa) | |||
ENO3 | enolase 3 (beta, muscle); Appears to have a function in striated muscle development and regeneration (434 aa) | |||
RIPK4 | receptor-interacting serine-threonine kinase 4; Involved in stratified epithelial development. It is a direct transcriptional target of TP63. Plays a role in NF-kappa-B activation (784 aa) | |||
UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 (170 aa) | |||
SLC37A1 | solute carrier family 37 (glycerol-3-phosphate transporter), member 1 (533 aa) | |||
ENO4 | enolase family member 4 (628 aa) | |||
EPRS | glutamyl-prolyl-tRNA synthetase (1512 aa) | |||
DIS3 | DIS3 mitotic control homolog (S. cerevisiae) (958 aa) | |||
GALT | galactose-1-phosphate uridylyltransferase (379 aa) | |||
CDK1 | cyclin-dependent kinase 1; Plays a key role in the control of the eukaryotic cell cycle by modulating the centrosome cycle as well as mitotic onset; promotes G2-M transition, and regulates G1 progress and G1-S transition via association with multiple interphase cyclins. Required in higher cells for entry into S-phase and mitosis. Phosphorylates PARVA/actopaxin, APC, AMPH, APC, BARD1, Bcl- xL/BCL2L1, BRCA2, CALD1, CASP8, CDC7, CDC20, CDC25A, CDC25C, CC2D1A, CSNK2 proteins/CKII, FZR1/CDH1, CDK7, CEBPB, CHAMP1, DMD/dystrophin, EEF1 proteins/EF-1, EZH2, KIF11/EG5, EGFR, FANCG, FOS, GFAP, G [...] (297 aa) | |||
GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (753 aa) | |||
UAP1L1 | UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 (507 aa) | |||
HELZ2 | helicase with zinc finger 2, transcriptional coactivator; Helicase that acts as a transcriptional coactivator for a number of nuclear receptors including PPARA, PPARG, THRA, THRB and RXRA (2649 aa) | |||
PGM3 | phosphoglucomutase 3 (570 aa) | |||
UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2; Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through ’Lys-63’. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage (145 aa) | |||
ENSG00000258728 | Uncharacterized protein (280 aa) |