node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMDHD2 | GNPDA1 | ENSP00000391596 | ENSP00000311876 | amidohydrolase domain containing 2; Hydrolyzes the N-glycolyl group from N- glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | 0.753 |
AMDHD2 | GNPDA2 | ENSP00000391596 | ENSP00000295448 | amidohydrolase domain containing 2; Hydrolyzes the N-glycolyl group from N- glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded | glucosamine-6-phosphate deaminase 2 | 0.897 |
AMDHD2 | H6PD | ENSP00000391596 | ENSP00000366620 | amidohydrolase domain containing 2; Hydrolyzes the N-glycolyl group from N- glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase); Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates | 0.718 |
AMDHD2 | PGLS | ENSP00000391596 | ENSP00000252603 | amidohydrolase domain containing 2; Hydrolyzes the N-glycolyl group from N- glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate | 0.663 |
AMDHD2 | UBC | ENSP00000391596 | ENSP00000344818 | amidohydrolase domain containing 2; Hydrolyzes the N-glycolyl group from N- glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded | ubiquitin C | 0.620 |
GNPDA1 | AMDHD2 | ENSP00000311876 | ENSP00000391596 | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | amidohydrolase domain containing 2; Hydrolyzes the N-glycolyl group from N- glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded | 0.753 |
GNPDA1 | GNPDA2 | ENSP00000311876 | ENSP00000295448 | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | glucosamine-6-phosphate deaminase 2 | 0.418 |
GNPDA1 | H6PD | ENSP00000311876 | ENSP00000366620 | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase); Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates | 0.903 |
GNPDA1 | PGLS | ENSP00000311876 | ENSP00000252603 | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate | 0.860 |
GNPDA1 | UBC | ENSP00000311876 | ENSP00000344818 | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | ubiquitin C | 0.863 |
GNPDA2 | AMDHD2 | ENSP00000295448 | ENSP00000391596 | glucosamine-6-phosphate deaminase 2 | amidohydrolase domain containing 2; Hydrolyzes the N-glycolyl group from N- glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded | 0.897 |
GNPDA2 | GNPDA1 | ENSP00000295448 | ENSP00000311876 | glucosamine-6-phosphate deaminase 2 | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | 0.418 |
GNPDA2 | H6PD | ENSP00000295448 | ENSP00000366620 | glucosamine-6-phosphate deaminase 2 | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase); Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates | 0.842 |
GNPDA2 | PGLS | ENSP00000295448 | ENSP00000252603 | glucosamine-6-phosphate deaminase 2 | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate | 0.683 |
GNPDA2 | UBC | ENSP00000295448 | ENSP00000344818 | glucosamine-6-phosphate deaminase 2 | ubiquitin C | 0.807 |
H6PD | AMDHD2 | ENSP00000366620 | ENSP00000391596 | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase); Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates | amidohydrolase domain containing 2; Hydrolyzes the N-glycolyl group from N- glycolylglucosamine 6-phosphate (GlcNGc-6-P) in the N- glycolylneuraminic acid (Neu5Gc) degradation pathway. Although human is not able to catalyze formation of Neu5Gc due to the inactive CMAHP enzyme, Neu5Gc is present in food and must be degraded | 0.718 |
H6PD | GNPDA1 | ENSP00000366620 | ENSP00000311876 | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase); Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates | glucosamine-6-phosphate deaminase 1; Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity) | 0.903 |
H6PD | GNPDA2 | ENSP00000366620 | ENSP00000295448 | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase); Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates | glucosamine-6-phosphate deaminase 2 | 0.842 |
H6PD | PGLS | ENSP00000366620 | ENSP00000252603 | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase); Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates | 6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate | 0.960 |
H6PD | UBC | ENSP00000366620 | ENSP00000344818 | hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase); Oxidizes glucose-6-phosphate and glucose, as well as other hexose-6-phosphates | ubiquitin C | 0.591 |