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SHPK | sedoheptulokinase; Acts as a modulator of macrophage activation through control of glucose metabolism (By similarity) (478 aa) | |||
WDFY1 | WD repeat and FYVE domain containing 1 (410 aa) | |||
KLHL24 | kelch-like 24 (Drosophila); Specifically reduces kainate receptor-mediated currents in hippocampal neurons, most probably by modulating channel properties (By similarity) (600 aa) | |||
NBN | nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3’-5’ exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. NBN modulate the DNA damage signal sensing by recru [...] (754 aa) | |||
MARS2 | methionyl-tRNA synthetase 2, mitochondrial (593 aa) | |||
MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae); Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand- specific 3’-5’ exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA li [...] (708 aa) | |||
FAM219A | family with sequence similarity 219, member A (185 aa) | |||
FBXO10 | F-box protein 10; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) (956 aa) |