4 items (Homo sapiens) - STRING network view

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Your Input:
	RXFP1	relaxin/insulin-like family peptide receptor 1; Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP (757 aa)
	RXFP3	relaxin/insulin-like family peptide receptor 3; Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation (469 aa)
	RXFP4	relaxin/insulin-like family peptide receptor 4; High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation (374 aa)
	RLN3	relaxin 3; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142) (142 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
RLN3	RXFP1	ENSP00000397415	ENSP00000303248	relaxin 3; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142)	relaxin/insulin-like family peptide receptor 1; Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP	0.994
RLN3	RXFP3	ENSP00000397415	ENSP00000328708	relaxin 3; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142)	relaxin/insulin-like family peptide receptor 3; Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation	0.998
RLN3	RXFP4	ENSP00000397415	ENSP00000357301	relaxin 3; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142)	relaxin/insulin-like family peptide receptor 4; High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation	0.994
RXFP1	RLN3	ENSP00000303248	ENSP00000397415	relaxin/insulin-like family peptide receptor 1; Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP	relaxin 3; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142)	0.994
RXFP1	RXFP3	ENSP00000303248	ENSP00000328708	relaxin/insulin-like family peptide receptor 1; Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP	relaxin/insulin-like family peptide receptor 3; Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation	0.884
RXFP1	RXFP4	ENSP00000303248	ENSP00000357301	relaxin/insulin-like family peptide receptor 1; Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP	relaxin/insulin-like family peptide receptor 4; High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation	0.915
RXFP3	RLN3	ENSP00000328708	ENSP00000397415	relaxin/insulin-like family peptide receptor 3; Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation	relaxin 3; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142)	0.998
RXFP3	RXFP1	ENSP00000328708	ENSP00000303248	relaxin/insulin-like family peptide receptor 3; Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation	relaxin/insulin-like family peptide receptor 1; Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP	0.884
RXFP3	RXFP4	ENSP00000328708	ENSP00000357301	relaxin/insulin-like family peptide receptor 3; Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation	relaxin/insulin-like family peptide receptor 4; High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation	0.909
RXFP4	RLN3	ENSP00000357301	ENSP00000397415	relaxin/insulin-like family peptide receptor 4; High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation	relaxin 3; May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142)	0.994
RXFP4	RXFP1	ENSP00000357301	ENSP00000303248	relaxin/insulin-like family peptide receptor 4; High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation	relaxin/insulin-like family peptide receptor 1; Receptor for relaxins. The activity of this receptor is mediated by G proteins leading to stimulation of adenylate cyclase and an increase of cAMP. Binding of the ligand may also activate a tyrosine kinase pathway that inhibits the activity of a phosphodiesterase that degrades cAMP	0.915
RXFP4	RXFP3	ENSP00000357301	ENSP00000328708	relaxin/insulin-like family peptide receptor 4; High affinity receptor for INSL5. Also acts as receptor for RLN3/relaxin-3, as well as bradykinin and kallidin. Binding of the ligand inhibit cAMP accumulation	relaxin/insulin-like family peptide receptor 3; Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation	0.909

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