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SFT2D2 SFT2D2 GOLGA3 GOLGA3 COG2 COG2 SFT2D3 SFT2D3 COG5 COG5 COG1 COG1 GOLT1B GOLT1B COG7 COG7 COG4 COG4 GOLT1A GOLT1A COG3 COG3 SFT2D1 SFT2D1 COG6 COG6 COG8 COG8 ENSG00000261576 ENSG00000261576 ENSG00000260371 ENSG00000260371 WRB WRB RCE1 RCE1 ARFRP1 ARFRP1 SYS1 SYS1 TBC1D22B TBC1D22B TBC1D22A TBC1D22A STX16 STX16 ARL1 ARL1 ARL16 ARL16 ARL13B ARL13B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
GOLGA3golgin A3; Golgi auto-antigen; probably involved in maintaining Golgi structure (1498 aa)
GOLT1Bgolgi transport 1B; May be involved in fusion of ER-derived transport vesicles with the Golgi complex (138 aa)
SYS1SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae); Involved in protein trafficking. May serve as a receptor for ARFRP1 (156 aa)
COG3component of oligomeric golgi complex 3; Involved in ER-Golgi transport (828 aa)
ARL1ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus (181 aa)
SFT2D2SFT2 domain containing 2; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (By similarity) (160 aa)
COG5component of oligomeric golgi complex 5; Required for normal Golgi function (By similarity) (860 aa)
COG1component of oligomeric golgi complex 1; Required for normal Golgi function (By similarity) (980 aa)
COG7component of oligomeric golgi complex 7; Required for normal Golgi function (By similarity) (770 aa)
COG8component of oligomeric golgi complex 8; Required for normal Golgi function (By similarity) (612 aa)
GOLT1Agolgi transport 1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex (132 aa)
RCE1RCE1 homolog, prenyl protein protease (S. cerevisiae); Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins. Seems to be able to process K-Ras, N-Ras, H-Ras, RAP1B and G-gamma-1 (329 aa)
SFT2D3SFT2 domain containing 3; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (By similarity) (215 aa)
COG4component of oligomeric golgi complex 4; Required for normal Golgi function. Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with SCFD1 (789 aa)
ARFRP1ADP-ribosylation factor related protein 1; Possibly involved in plasma membrane-related signaling events (201 aa)
WRBtryptophan rich basic protein; Receptor for ASNA1/TRC40-mediated insertion of tail- anchored (TA) proteins into the ER membrane (174 aa)
TBC1D22ATBC1 domain family, member 22A (517 aa)
SFT2D1SFT2 domain containing 1; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex (By similarity) (159 aa)
COG2component of oligomeric golgi complex 2; Required for normal Golgi morphology and function (738 aa)
STX16syntaxin 16 (325 aa)
TBC1D22BTBC1 domain family, member 22B; May act as a GTPase-activating protein for Rab family protein(s) (By similarity) (505 aa)
ARL13BADP-ribosylation factor-like 13B (428 aa)
ARL16ADP-ribosylation factor-like 16 (197 aa)
COG6component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity) (657 aa)
ENSG00000260371Uncharacterized protein (156 aa)
ENSG00000261576Uncharacterized protein (164 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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