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ARF5 | ADP-ribosylation factor 5; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (180 aa) | |||
CAMK1G | calcium/calmodulin-dependent protein kinase IG; Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription factor CREB1 (By similarity) (476 aa) | |||
VAMP3 | vesicle-associated membrane protein 3; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network (100 aa) | |||
STX1B | syntaxin 1B; Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm (By similarity) (288 aa) | |||
UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative); Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer ’Lys-11’ and ’Lys-48’-linked polyubiquitination (147 aa) | |||
STX1A | syntaxin 1A (brain) (288 aa) | |||
VAMP4 | vesicle-associated membrane protein 4; Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule (141 aa) | |||
STX6 | syntaxin 6; Involved in intracellular vesicle trafficking (255 aa) | |||
ARF4 | ADP-ribosylation factor 4; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (180 aa) | |||
VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2); Involved in the targeting and/or fusion of transport vesicles to their target membrane (116 aa) | |||
STX4 | syntaxin 4; Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones (297 aa) | |||
STX19 | syntaxin 19 (294 aa) | |||
STX3 | syntaxin 3; Potentially involved in docking of synaptic vesicles at presynaptic active zones (289 aa) | |||
BZRAP1 | benzodiazapine receptor (peripheral) associated protein 1 (1857 aa) | |||
DRD2 | dopamine receptor D2; Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase (By similarity) (443 aa) | |||
DMD | dystrophin (3685 aa) | |||
STX11 | syntaxin 11; SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network (287 aa) | |||
UBE2U | ubiquitin-conjugating enzyme E2U (putative); Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity) (226 aa) | |||
STX2 | syntaxin 2; Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm (288 aa) | |||
SRPK2 | SRSF protein kinase 2; Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and [...] (699 aa) | |||
VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1); Involved in the targeting and/or fusion of transport vesicles to their target membrane (118 aa) | |||
CAPS2 | calcyphosine 2 (557 aa) | |||
CADPS2 | Ca++-dependent secretion activator 2 (1296 aa) | |||
BDNF | brain-derived neurotrophic factor (329 aa) | |||
GOLGA2 | golgin A2; Golgi auto-antigen; probably involved in maintaining cis-Golgi structure (1002 aa) | |||
ENSG00000263620 | Uncharacterized protein (121 aa) |