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SEC14L3 | SEC14-like 3 (S. cerevisiae); Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids (400 aa) | |||
BYSL | bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos (437 aa) | |||
SEC14L5 | SEC14-like 5 (S. cerevisiae) (696 aa) | |||
SEC14L4 | SEC14-like 4 (S. cerevisiae); Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids (406 aa) | |||
TTPA | tocopherol (alpha) transfer protein; Binds alpha-tocopherol and enhances its transfer between separate membranes (278 aa) | |||
TTPAL | tocopherol (alpha) transfer protein-like; May act as a protein that binds a hydrophobic ligand (Potential) (342 aa) | |||
MCM2 | minichromosome maintenance complex component 2; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ’once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute dif [...] (904 aa) | |||
RLBP1 | retinaldehyde binding protein 1; Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the ’visual cycle’ (317 aa) | |||
CLVS2 | clavesin 2; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (327 aa) | |||
NXF1 | nuclear RNA export factor 1; Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 (619 aa) | |||
DHX37 | DEAH (Asp-Glu-Ala-His) box polypeptide 37 (1157 aa) | |||
MCM9 | minichromosome maintenance complex component 9; Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8- MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart (1143 aa) | |||
SEC14L2 | SEC14-like 2 (S. cerevisiae); Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell (403 aa) | |||
CLVS1 | clavesin 1; Required for normal morphology of late endosomes and/or lysosomes in neurons (By similarity). Binds phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (354 aa) | |||
NXF2 | nuclear RNA export factor 2 (626 aa) | |||
DMTF1 | cyclin D binding myb-like transcription factor 1 (760 aa) | |||
TTF1 | transcription termination factor, RNA polymerase I; Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity (905 aa) | |||
NXF2B | nuclear RNA export factor 2B; Involved in the export of mRNA from the nucleus to the cytoplasm (626 aa) | |||
SEC14L1 | SEC14-like 1 (S. cerevisiae) (719 aa) | |||
SEC14L6 | SEC14-like 6 (S. cerevisiae) (397 aa) | |||
WBSCR22 | Williams Beuren syndrome chromosome region 22 (298 aa) | |||
ENSG00000249590 | Uncharacterized protein (338 aa) | |||
NXF5 | nuclear RNA export factor 5 (365 aa) | |||
TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae); Participates both in methylation of protein and tRNA species. The heterodimer with HEMK2/N6AMT1 catalyzes N5- methylation of ETF1 on ’Gln-185’, using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species (125 aa) | |||
RPS15 | ribosomal protein S15 (145 aa) | |||
ENSG00000268412 | Uncharacterized protein (135 aa) |