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HMOX1 | heme oxygenase (decycling) 1; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed (288 aa) | |||
FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae); Promotes the fragmentation of the mitochondrial network and its perinuclear clustering. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission (152 aa) | |||
TMEM14C | transmembrane protein 14C; Required for normal heme biosynthesis (By similarity) (112 aa) | |||
STBD1 | starch binding domain 1; May have the capability to bind to carbohydrates (Potential) (358 aa) | |||
MTX2 | metaxin 2; Involved in transport of proteins into the mitochondrion (263 aa) | |||
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining th [...] (1089 aa) | |||
SLC41A2 | solute carrier family 41, member 2; Acts as a plasma-membrane magnesium transporter (573 aa) | |||
UPK2 | uroplakin 2; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in regulating the assembly of the AUM (By similarity) (184 aa) | |||
CLDN8 | claudin 8; Plays a major role in tight junction-specific obliteration of the intercellular space (By similarity) (225 aa) | |||
FTCD | formiminotransferase cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool (541 aa) | |||
C17orf62 | chromosome 17 open reading frame 62 (187 aa) | |||
MMP14 | matrix metallopeptidase 14 (membrane-inserted); Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15 (582 aa) | |||
NRIP3 | nuclear receptor interacting protein 3 (241 aa) | |||
MS4A1 | membrane-spanning 4-domains, subfamily A, member 1; This protein may be involved in the regulation of B-cell activation and proliferation (297 aa) | |||
ADIPOQ | adiponectin, C1Q and collagen domain containing; Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play [...] (244 aa) | |||
ABHD1 | abhydrolase domain containing 1 (405 aa) | |||
CCDC87 | coiled-coil domain containing 87 (849 aa) | |||
LARP1 | La ribonucleoprotein domain family, member 1 (1019 aa) | |||
RTP2 | receptor (chemosensory) transporter protein 2; Specifically promotes functional cell surface expression of olfactory receptors, but not of other GPCRs (By similarity) (225 aa) | |||
LHFPL5 | lipoma HMGIC fusion partner-like 5; May function in hair bundle morphogenesis (By similarity) (219 aa) | |||
GALNT2 | UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D- galactosamine residue to a serine or threonine residue on the protein receptor. Has a broad spectrum of substrates for peptides such as EA2, Muc5AC, Muc1a, Muc1b. Probably involved in O-linked glycosylation of the immunoglobulin A1 (IgA1) hinge region (571 aa) | |||
CRABP2 | cellular retinoic acid binding protein 2; Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors (138 aa) | |||
FRA10AC1 | fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 (315 aa) | |||
SERP2 | stress-associated endoplasmic reticulum protein family member 2; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation (Potential) (65 aa) | |||
NSG1 | Neuron-specific protein family member 1 (185 aa) | |||
CCDC155 | coiled-coil domain containing 155; May be involved in meiotic chromosome dynamics and homolog pairing (By similarity) (562 aa) |