Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP13A2 | VPS35 | ENSP00000327214 | ENSP00000299138 | ATPase type 13A2; May play a role in intracellular cation homeostasis and the maintenance of neuronal integrity | vacuolar protein sorting 35 homolog (S. cerevisiae) | 0.554 |
GTF2E1 | OXR1 | ENSP00000283875 | ENSP00000405424 | general transcription factor IIE, polypeptide 1, alpha 56kDa; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase | oxidation resistance 1 | 0.414 |
KEAP1 | OXR1 | ENSP00000171111 | ENSP00000405424 | kelch-like ECH-associated protein 1; Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome | oxidation resistance 1 | 0.499 |
NMI | OXR1 | ENSP00000243346 | ENSP00000405424 | N-myc (and STAT) interactor; May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5 | oxidation resistance 1 | 0.412 |
NMI | TOLLIP | ENSP00000243346 | ENSP00000314733 | N-myc (and STAT) interactor; May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5 | toll interacting protein; Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity | 0.538 |
OXR1 | GTF2E1 | ENSP00000405424 | ENSP00000283875 | oxidation resistance 1 | general transcription factor IIE, polypeptide 1, alpha 56kDa; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase | 0.414 |
OXR1 | KEAP1 | ENSP00000405424 | ENSP00000171111 | oxidation resistance 1 | kelch-like ECH-associated protein 1; Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome | 0.499 |
OXR1 | NMI | ENSP00000405424 | ENSP00000243346 | oxidation resistance 1 | N-myc (and STAT) interactor; May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5 | 0.412 |
OXR1 | RPL24 | ENSP00000405424 | ENSP00000377640 | oxidation resistance 1 | ribosomal protein L24 | 0.420 |
OXR1 | TOLLIP | ENSP00000405424 | ENSP00000314733 | oxidation resistance 1 | toll interacting protein; Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity | 0.538 |
OXR1 | VPS35 | ENSP00000405424 | ENSP00000299138 | oxidation resistance 1 | vacuolar protein sorting 35 homolog (S. cerevisiae) | 0.509 |
RPL24 | OXR1 | ENSP00000377640 | ENSP00000405424 | ribosomal protein L24 | oxidation resistance 1 | 0.420 |
TOLLIP | NMI | ENSP00000314733 | ENSP00000243346 | toll interacting protein; Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity | N-myc (and STAT) interactor; May be involved in augmenting coactivator protein recruitment to a group of sequence-specific transcription factors. Augments cytokine-mediated STAT transcription. Enhances CBP/p300 coactivator protein recruitment to STAT1 and STAT5 | 0.538 |
TOLLIP | OXR1 | ENSP00000314733 | ENSP00000405424 | toll interacting protein; Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity | oxidation resistance 1 | 0.538 |
TOLLIP | VPS35 | ENSP00000314733 | ENSP00000299138 | toll interacting protein; Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity | vacuolar protein sorting 35 homolog (S. cerevisiae) | 0.476 |
VPS35 | ATP13A2 | ENSP00000299138 | ENSP00000327214 | vacuolar protein sorting 35 homolog (S. cerevisiae) | ATPase type 13A2; May play a role in intracellular cation homeostasis and the maintenance of neuronal integrity | 0.554 |
VPS35 | OXR1 | ENSP00000299138 | ENSP00000405424 | vacuolar protein sorting 35 homolog (S. cerevisiae) | oxidation resistance 1 | 0.509 |
VPS35 | TOLLIP | ENSP00000299138 | ENSP00000314733 | vacuolar protein sorting 35 homolog (S. cerevisiae) | toll interacting protein; Component of the signaling pathway of IL-1 and Toll-like receptors. Inhibits cell activation by microbial products. Recruits IRAK1 to the IL-1 receptor complex. Inhibits IRAK1 phosphorylation and kinase activity | 0.476 |