24 items (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	RPS16	ribosomal protein S16 (146 aa)
	MRPS9	mitochondrial ribosomal protein S9 (396 aa)
	CAD	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (2225 aa)
	NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit; The NAA10-NAA15 complex displays alpha (N-terminal) acetyltransferase activity that may be important for vascular, hematopoietic and neuronal growth and development. Required to control retinal neovascularization in adult ocular endothelial cells. In complex with XRCC6 and XRCC5 (Ku80), up-regulates transcription from the osteocalcin promoter (866 aa)
	RPS23	ribosomal protein S23 (143 aa)
	MRPL40	mitochondrial ribosomal protein L40 (206 aa)
	RPL9	ribosomal protein L9 (192 aa)
	RPLP1	ribosomal protein, large, P1; Plays an important role in the elongation step of protein synthesis (114 aa)
	RPL22L1	ribosomal protein L22-like 1 (122 aa)
	RPL22	ribosomal protein L22 (128 aa)
	RPL12	ribosomal protein L12; Binds directly to 26S ribosomal RNA (By similarity) (165 aa)
	RPL7A	ribosomal protein L7a (266 aa)
	PSAT1	phosphoserine aminotransferase 1; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) (370 aa)
	DNAJC2	DnaJ (Hsp40) homolog, subfamily C, member 2; Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone- component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb- repressed genes to an active state- specifically recruit [...] (621 aa)
	NAA16	N(alpha)-acetyltransferase 16, NatA auxiliary subunit; May belong to a complex displaying N-terminal acetyltransferase activity (By similarity) (864 aa)
	RPS6	ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (249 aa)
	MRPL2	mitochondrial ribosomal protein L2 (305 aa)
	RPL24	ribosomal protein L24 (157 aa)
	RPL23	ribosomal protein L23 (140 aa)
	RPL34	ribosomal protein L34 (117 aa)
	CPS1	carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell (1506 aa)
	METTL11B	methyltransferase like 11B; Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]- Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di- methylation of Pro in the Pro-Pro-Lys motif (By similarity) (283 aa)
	RPL37A	ribosomal protein L37a (92 aa)
	RPS19	ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits (145 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAD	CPS1	ENSP00000264705	ENSP00000402608	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell	0.999
CAD	DNAJC2	ENSP00000264705	ENSP00000368565	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	DnaJ (Hsp40) homolog, subfamily C, member 2; Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone- component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb- repressed genes to an active state- specifically recruit [...]	0.408
CAD	MRPL2	ENSP00000264705	ENSP00000373404	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	mitochondrial ribosomal protein L2	0.587
CAD	MRPS9	ENSP00000264705	ENSP00000258455	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	mitochondrial ribosomal protein S9	0.501
CAD	RPL12	ENSP00000264705	ENSP00000354739	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	ribosomal protein L12; Binds directly to 26S ribosomal RNA (By similarity)	0.405
CAD	RPL9	ENSP00000264705	ENSP00000346022	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	ribosomal protein L9	0.563
CAD	RPS16	ENSP00000264705	ENSP00000251453	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	ribosomal protein S16	0.501
CAD	RPS19	ENSP00000264705	ENSP00000470004	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	ribosomal protein S19; Required for pre-rRNA processing and maturation of 40S ribosomal subunits	0.406
CAD	RPS23	ENSP00000264705	ENSP00000296674	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	ribosomal protein S23	0.615
CAD	RPS6	ENSP00000264705	ENSP00000369757	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA	0.568
CPS1	CAD	ENSP00000402608	ENSP00000264705	carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	0.999
CPS1	RPS23	ENSP00000402608	ENSP00000296674	carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell	ribosomal protein S23	0.417
CPS1	RPS6	ENSP00000402608	ENSP00000369757	carbamoyl-phosphate synthase 1, mitochondrial; Involved in the urea cycle of ureotelic animals where the enzyme plays an important role in removing excess ammonia from the cell	ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA	0.430
DNAJC2	CAD	ENSP00000368565	ENSP00000264705	DnaJ (Hsp40) homolog, subfamily C, member 2; Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone- component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb- repressed genes to an active state- specifically recruit [...]	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	0.408
DNAJC2	RPL24	ENSP00000368565	ENSP00000377640	DnaJ (Hsp40) homolog, subfamily C, member 2; Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone- component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb- repressed genes to an active state- specifically recruit [...]	ribosomal protein L24	0.522
MRPL2	CAD	ENSP00000373404	ENSP00000264705	mitochondrial ribosomal protein L2	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase; This protein is a "fusion" protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase)	0.587
MRPL2	MRPL40	ENSP00000373404	ENSP00000333401	mitochondrial ribosomal protein L2	mitochondrial ribosomal protein L40	0.927
MRPL2	MRPS9	ENSP00000373404	ENSP00000258455	mitochondrial ribosomal protein L2	mitochondrial ribosomal protein S9	0.948
MRPL2	RPL12	ENSP00000373404	ENSP00000354739	mitochondrial ribosomal protein L2	ribosomal protein L12; Binds directly to 26S ribosomal RNA (By similarity)	0.974
MRPL2	RPL22	ENSP00000373404	ENSP00000346088	mitochondrial ribosomal protein L2	ribosomal protein L22	0.831

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