Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
ABCB4 ABCB4 ABCC4 ABCC4 ENSG00000250264 ENSG00000250264 ABCB5 ABCB5 ABCC12 ABCC12 ABCC3 ABCC3 APOA1 APOA1 ABCC9 ABCC9 ABCB11 ABCB11 ABCC8 ABCC8 APOA2 APOA2 ABCC10 ABCC10 ABCA13 ABCA13 ABCC6 ABCC6 TAP1 TAP1 TAP2 TAP2 RPS3 RPS3 ABCC5 ABCC5 ABCG2 ABCG2 ABCC1 ABCC1 ABCB9 ABCB9 ABCB10 ABCB10 ABCC11 ABCC11 ABCB8 ABCB8 ABCC2 ABCC2 ABCB1 ABCB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
ABCC6ATP-binding cassette, sub-family C (CFTR/MRP), member 6; May participate directly in the active transport of drugs into subcellular organelles or influence drug distribution indirectly. Transports glutathione conjugates as leukotriene-c4 (LTC4) and N-ethylmaleimide S-glutathione (NEM-GS) (1503 aa)
APOA1apolipoprotein A-I; Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility (267 aa)
ABCG2ATP-binding cassette, sub-family G (WHITE), member 2 (655 aa)
ABCC9ATP-binding cassette, sub-family C (CFTR/MRP), member 9; Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation (1549 aa)
ABCB11ATP-binding cassette, sub-family B (MDR/TAP), member 11; Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes (1321 aa)
ABCB4ATP-binding cassette, sub-family B (MDR/TAP), member 4; Mediates ATP-dependent export of organic anions and drugs from the cytoplasm. Hydrolyzes ATP with low efficiency. Not capable of conferring drug resistance. Mediates the translocation of phosphatidylcholine across the canalicular membrane of the hepatocyte (1286 aa)
ABCB1ATP-binding cassette, sub-family B (MDR/TAP), member 1; Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (1280 aa)
ABCB9ATP-binding cassette, sub-family B (MDR/TAP), member 9; ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored (766 aa)
ABCC3ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (1527 aa)
ABCC12ATP-binding cassette, sub-family C (CFTR/MRP), member 12; Probable transporter (By similarity) (1359 aa)
ABCC5ATP-binding cassette, sub-family C (CFTR/MRP), member 5 (1437 aa)
TAP1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) (808 aa)
ABCC11ATP-binding cassette, sub-family C (CFTR/MRP), member 11; Participates in physiological processes involving bile acids, conjugated steroids and cyclic nucleotides. Enhances the cellular extrusion of cAMP and cGMP. Stimulates the ATP-dependent uptake of a range of physiological and synthetic lipophilic anions, including the glutathione S-conjugates leukotriene C4 and dinitrophenyl S-glutathione, steroid sulfates such as dehydroepiandrosterone 3-sulfate (DHEAS) and estrone 3-sulfate, glucuronides such as estradiol 17-beta-D-glucuronide (E(2)17betaG), the monoanionic bile acids glycochola [...] (1382 aa)
ABCB8ATP-binding cassette, sub-family B (MDR/TAP), member 8 (718 aa)
ABCB10ATP-binding cassette, sub-family B (MDR/TAP), member 10; May mediate critical mitochondrial transport functions related to heme biosynthesis (By similarity) (738 aa)
APOA2apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism (100 aa)
ABCC2ATP-binding cassette, sub-family C (CFTR/MRP), member 2; Mediates hepatobiliary excretion of numerous organic anions. May function as a cellular cisplatin transporter (1545 aa)
ABCC10ATP-binding cassette, sub-family C (CFTR/MRP), member 10; ATP-dependent transporter probably involved in cellular detoxification through lipophilic anion extrusion (1492 aa)
TAP2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) (653 aa)
ABCC4ATP-binding cassette, sub-family C (CFTR/MRP), member 4; May be an organic anion pump relevant to cellular detoxification (1325 aa)
ABCC8ATP-binding cassette, sub-family C (CFTR/MRP), member 8; Putative subunit of the beta-cell ATP-sensitive potassium channel (KATP). Regulator of ATP-sensitive K(+) channels and insulin release (1581 aa)
ABCC1ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (1531 aa)
ABCB5ATP-binding cassette, sub-family B (MDR/TAP), member 5 (1257 aa)
ENSG00000250264Uncharacterized protein (843 aa)
ABCA13ATP-binding cassette, sub-family A (ABC1), member 13 (5058 aa)
RPS3ribosomal protein S3 (243 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: low (34%)