26 items (Homo sapiens) - STRING network view

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protein of unknown 3D structure

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Your Input:
	DVL2	dishevelled, dsh homolog 2 (Drosophila); Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity) (736 aa)
	RABAC1	Rab acceptor 1 (prenylated); General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI (By similarity) (185 aa)
	SYS1	SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae); Involved in protein trafficking. May serve as a receptor for ARFRP1 (156 aa)
	DCLK1	doublecortin-like kinase 1; Probable kinase that may be involved in a calcium- signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system (729 aa)
	ARL1	ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus (181 aa)
	RAB36	RAB36, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) (333 aa)
	SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1; Core component of the BAF (hSWI/SNF) complex. This ATP- dependent chromatin-remodeling complex plays important roles in cell proliferation and differentiation, in cellular antiviral activities and inhibition of tumor formation. The BAF complex is able to create a stable, altered form of chromatin that constrains fewer negative supercoils than normal. This change in supercoiling would be due to the conversion of up to one-half of the nucleosomes on polynucleosomal arrays into asymmetric st [...] (385 aa)
	RPS27A	ribosomal protein S27a (156 aa)
	RAB41	RAB41, member RAS oncogene family (221 aa)
	RAB6B	RAB6B, member RAS oncogene family; Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells (208 aa)
	DCLK2	doublecortin-like kinase 2; Protein kinase with a significantly reduced C(a2+)/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity) (783 aa)
	COG8	component of oligomeric golgi complex 8; Required for normal Golgi function (By similarity) (612 aa)
	RAB6A	RAB6A, member RAS oncogene family; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity (208 aa)
	DVL3	dishevelled, dsh homolog 3 (Drosophila); May play a role in the signal transduction pathway mediated by multiple Wnt genes (716 aa)
	TBC1D22A	TBC1 domain family, member 22A (517 aa)
	UBC	ubiquitin C (685 aa)
	ATP13A1	ATPase type 13A1 (1204 aa)
	TBC1D22B	TBC1 domain family, member 22B; May act as a GTPase-activating protein for Rab family protein(s) (By similarity) (505 aa)
	DVL1	dishevelled, dsh homolog 1 (Drosophila); Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ) (670 aa)
	ARL16	ADP-ribosylation factor-like 16 (197 aa)
	RAB6C	RAB6C, member RAS oncogene family; May be involved in the regulation of centrosome duplication and cell cycle progression (254 aa)
	DCLK3	doublecortin-like kinase 3 (648 aa)
	RAB34	RAB34, member RAS oncogene family; Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes (316 aa)
	KIAA1432	KIAA1432 (1423 aa)
	ENSG00000260371	Uncharacterized protein (156 aa)
	ENSG00000261576	Uncharacterized protein (164 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL1	KIAA1432	ENSP00000261636	ENSP00000416696	ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus	KIAA1432	0.693
ARL1	RAB34	ENSP00000261636	ENSP00000410403	ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus	RAB34, member RAS oncogene family; Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes	0.654
ARL1	RAB36	ENSP00000261636	ENSP00000263116	ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus	RAB36, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity)	0.654
ARL1	RAB41	ENSP00000261636	ENSP00000276066	ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus	RAB41, member RAS oncogene family	0.782
ARL1	RAB6A	ENSP00000261636	ENSP00000311449	ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus	RAB6A, member RAS oncogene family; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity	0.782
ARL1	RAB6B	ENSP00000261636	ENSP00000285208	ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus	RAB6B, member RAS oncogene family; Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells	0.782
ARL1	RAB6C	ENSP00000261636	ENSP00000387307	ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus	RAB6C, member RAS oncogene family; May be involved in the regulation of centrosome duplication and cell cycle progression	0.782
ARL1	TBC1D22A	ENSP00000261636	ENSP00000336724	ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus	TBC1 domain family, member 22A	0.693
ARL1	TBC1D22B	ENSP00000261636	ENSP00000362590	ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus	TBC1 domain family, member 22B; May act as a GTPase-activating protein for Rab family protein(s) (By similarity)	0.693
ARL1	UBC	ENSP00000261636	ENSP00000344818	ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus	ubiquitin C	0.725
ARL16	KIAA1432	ENSP00000380635	ENSP00000416696	ADP-ribosylation factor-like 16	KIAA1432	0.693
ARL16	RAB34	ENSP00000380635	ENSP00000410403	ADP-ribosylation factor-like 16	RAB34, member RAS oncogene family; Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes	0.654
ARL16	RAB36	ENSP00000380635	ENSP00000263116	ADP-ribosylation factor-like 16	RAB36, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity)	0.654
ARL16	RAB41	ENSP00000380635	ENSP00000276066	ADP-ribosylation factor-like 16	RAB41, member RAS oncogene family	0.654
ARL16	RAB6A	ENSP00000380635	ENSP00000311449	ADP-ribosylation factor-like 16	RAB6A, member RAS oncogene family; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity	0.654
ARL16	RAB6B	ENSP00000380635	ENSP00000285208	ADP-ribosylation factor-like 16	RAB6B, member RAS oncogene family; Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells	0.654
ARL16	RAB6C	ENSP00000380635	ENSP00000387307	ADP-ribosylation factor-like 16	RAB6C, member RAS oncogene family; May be involved in the regulation of centrosome duplication and cell cycle progression	0.654
ARL16	TBC1D22A	ENSP00000380635	ENSP00000336724	ADP-ribosylation factor-like 16	TBC1 domain family, member 22A	0.613
ARL16	TBC1D22B	ENSP00000380635	ENSP00000362590	ADP-ribosylation factor-like 16	TBC1 domain family, member 22B; May act as a GTPase-activating protein for Rab family protein(s) (By similarity)	0.613
ARL16	UBC	ENSP00000380635	ENSP00000344818	ADP-ribosylation factor-like 16	ubiquitin C	0.424

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