node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AZGP1 | B2M | ENSP00000292401 | ENSP00000452780 | alpha-2-glycoprotein 1, zinc-binding; Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | 0.610 |
AZGP1 | MR1 | ENSP00000292401 | ENSP00000356552 | alpha-2-glycoprotein 1, zinc-binding; Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids | major histocompatibility complex, class I-related | 0.402 |
AZGP1 | UBC | ENSP00000292401 | ENSP00000344818 | alpha-2-glycoprotein 1, zinc-binding; Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids | ubiquitin C | 0.491 |
B2M | AZGP1 | ENSP00000452780 | ENSP00000292401 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | alpha-2-glycoprotein 1, zinc-binding; Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers. May bind polyunsaturated fatty acids | 0.610 |
B2M | HFE | ENSP00000452780 | ENSP00000417404 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | hemochromatosis | 0.998 |
B2M | HLA-A | ENSP00000452780 | ENSP00000366005 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | major histocompatibility complex, class I, A; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.998 |
B2M | HLA-B | ENSP00000452780 | ENSP00000399168 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | major histocompatibility complex, class I, B; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.999 |
B2M | HLA-C | ENSP00000452780 | ENSP00000365402 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | major histocompatibility complex, class I, C; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.986 |
B2M | HLA-G | ENSP00000452780 | ENSP00000353472 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | major histocompatibility complex, class I, G; Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells | 0.924 |
B2M | MR1 | ENSP00000452780 | ENSP00000356552 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | major histocompatibility complex, class I-related | 0.985 |
B2M | TF | ENSP00000452780 | ENSP00000385834 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | transferrin; Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation | 0.538 |
B2M | TFRC | ENSP00000452780 | ENSP00000353224 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | transferrin receptor (p90, CD71); Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin f [...] | 0.975 |
B2M | UBC | ENSP00000452780 | ENSP00000344818 | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | ubiquitin C | 0.790 |
HFE | B2M | ENSP00000417404 | ENSP00000452780 | hemochromatosis | beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system (By similarity) | 0.998 |
HFE | HLA-A | ENSP00000417404 | ENSP00000366005 | hemochromatosis | major histocompatibility complex, class I, A; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.559 |
HFE | HLA-B | ENSP00000417404 | ENSP00000399168 | hemochromatosis | major histocompatibility complex, class I, B; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.561 |
HFE | HLA-C | ENSP00000417404 | ENSP00000365402 | hemochromatosis | major histocompatibility complex, class I, C; Involved in the presentation of foreign antigens to the immune system (By similarity) | 0.544 |
HFE | HLA-G | ENSP00000417404 | ENSP00000353472 | hemochromatosis | major histocompatibility complex, class I, G; Involved in the presentation of foreign antigens to the immune system. Plays a role in maternal tolerance of the fetus by mediating protection from the deleterious effects of natural killer cells, cytotoxic T-lymphocytes, macrophages and mononuclear cells | 0.559 |
HFE | HSPA5 | ENSP00000417404 | ENSP00000324173 | hemochromatosis | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER | 0.570 |
HFE | MR1 | ENSP00000417404 | ENSP00000356552 | hemochromatosis | major histocompatibility complex, class I-related | 0.541 |