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STRINGSTRING
FAM18B1 FAM18B1 YIPF1 YIPF1 FAM18A FAM18A RAB33B RAB33B RAB33A RAB33A FAM18B2 FAM18B2 YIPF2 YIPF2 YIPF6 YIPF6 RAB1A RAB1A YIF1B YIF1B ENSG00000259024 ENSG00000259024 YIF1A YIF1A RAB1B RAB1B YIPF7 YIPF7 RAB43 RAB43 YIPF5 YIPF5 RAB19 RAB19 RABL6 RABL6 RAB5B RAB5B RAB5C RAB5C CLN8 CLN8 STX6 STX6 STX8 STX8 STX10 STX10 RAB5A RAB5A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
YIPF1Yip1 domain family, member 1 (306 aa)
FAM18B2family with sequence similarity 18, member B2 (276 aa)
YIPF2Yip1 domain family, member 2 (316 aa)
RAB33ARAB33A, member RAS oncogene family (237 aa)
STX6syntaxin 6; Involved in intracellular vesicle trafficking (255 aa)
RAB5ARAB5A, member RAS oncogene family; Required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension (215 aa)
YIPF5Yip1 domain family, member 5; Plays a role in transport between endoplasmic reticulum and Golgi (257 aa)
FAM18Afamily with sequence similarity 18, member A (213 aa)
STX8syntaxin 8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER (236 aa)
FAM18B1family with sequence similarity 18, member B1 (205 aa)
RAB33BRAB33B, member RAS oncogene family; Protein transport. Acts, in coordination with RAB6A, to regulate intra-Golgi retrograde trafficking. It is involved in autophagy, acting as a modulator of autophagosome formation (229 aa)
RAB1BRAB1B, member RAS oncogene family; Protein transport. Regulates vesicular transport between the endoplasmic reticulum and successive Golgi compartments (201 aa)
RAB43RAB43, member RAS oncogene family; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport o [...] (212 aa)
CLN8ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation); Could play a role in cell proliferation during neuronal differentiation and in protection against cell death (286 aa)
YIPF7Yip1 domain family, member 7 (280 aa)
YIF1BYip1 interacting factor homolog B (S. cerevisiae) (314 aa)
RAB5CRAB5C, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) (216 aa)
RAB19RAB19, member RAS oncogene family (217 aa)
RAB5BRAB5B, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) (215 aa)
RABL6RAB, member RAS oncogene family-like 6 (730 aa)
YIF1AYip1 interacting factor homolog A (S. cerevisiae); Possible role in transport between endoplasmic reticulum and Golgi (293 aa)
RAB1ARAB1A, member RAS oncogene family; Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity (205 aa)
YIPF6Yip1 domain family, member 6 (236 aa)
ENSG00000259024FAM18B2-CDRT4 readthrough (164 aa)
STX10syntaxin 10; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network (249 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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