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BRD1 | bromodomain containing 1; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (1058 aa) | |||
KAT2A | K(lysine) acetyltransferase 2A; Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Acetylation of histones gives a specific tag for epigenetic transcription activation. Has significant histone acetyltransferase activity with core histones, but not with nucleosome core particles. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat’s transactivating activity and may help inducing chromatin remodeling of proviral genes. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4 (837 aa) | |||
HIST1H4G | histone cluster 1, H4g; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity) (98 aa) | |||
CECR2 | cat eye syndrome chromosome region, candidate 2; Part of the CERF (CECR2-containing-remodeling factor) complex, which facilitates the perturbation of chromatin structure in an ATP-dependent manner. May be involved through its interaction with LRPPRC in the integration of cytoskeletal network with vesicular trafficking, nucleocytosolic shuttling, transcription, chromosome remodeling and cytokinesis (1443 aa) | |||
KAT2B | K(lysine) acetyltransferase 2B; Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat. Regulates Tat’s transactivating activity and may help inducing chromatin remodeling of proviral genes (832 aa) | |||
HIST1H4H | histone cluster 1, H4h (103 aa) | |||
DACH1 | dachshund homolog 1 (Drosophila) (708 aa) | |||
HIST1H4D | histone cluster 1, H4d (103 aa) | |||
HIST1H4I | histone cluster 1, H4i (103 aa) | |||
HIST1H4J | histone cluster 1, H4j (103 aa) | |||
HIST1H4L | histone cluster 1, H4l (103 aa) | |||
HIST1H4K | histone cluster 1, H4k (103 aa) | |||
BRPF3 | bromodomain and PHD finger containing, 3; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity (1205 aa) | |||
HIST4H4 | histone cluster 4, H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (103 aa) | |||
HIST1H4A | histone cluster 1, H4a (103 aa) | |||
HIST1H4E | histone cluster 1, H4e (103 aa) | |||
HIST2H4B | histone cluster 2, H4b (103 aa) | |||
HIST2H4A | histone cluster 2, H4a (103 aa) | |||
DACH2 | dachshund homolog 2 (Drosophila); Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator for SIX1 and SIX6. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Is recruited with SIX6 to the p27Kip1 promoter in embryonal retina. SIX6 corepression seems also to involve NCOR1, TBL1, HDAC1 and HDAC3. May be involved together with PAX3, SIX1, and EYA2 in regulation of myogenesis. In the developing somite, expression of DACH2 and PAX3 is regulated by [...] (599 aa) | |||
HIST1H4B | histone cluster 1, H4b (103 aa) | |||
HIST1H4F | histone cluster 1, H4f (103 aa) | |||
HIST1H4C | histone cluster 1, H4c (103 aa) | |||
ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila); Histone methyltransferase specifically methylating ’Lys- 36’ of histone H3 (H3K36me) (2964 aa) | |||
TSPYL6 | TSPY-like 6 (410 aa) | |||
ENSG00000267261 | Ras-related protein Rab-5C (282 aa) |