node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CST7 | CTSB | ENSP00000420384 | ENSP00000342070 | cystatin F (leukocystatin); Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system | cathepsin B; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis | 0.734 |
CST7 | CTSC | ENSP00000420384 | ENSP00000227266 | cystatin F (leukocystatin); Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system | cathepsin C | 0.628 |
CST7 | CTSL1 | ENSP00000420384 | ENSP00000345344 | cystatin F (leukocystatin); Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system | cathepsin L1; Important for the overall degradation of proteins in lysosomes | 0.665 |
CST7 | CTSS | ENSP00000420384 | ENSP00000357981 | cystatin F (leukocystatin); Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system | cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N | 0.475 |
CTSB | CST7 | ENSP00000342070 | ENSP00000420384 | cathepsin B; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis | cystatin F (leukocystatin); Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system | 0.734 |
CTSB | CTSL1 | ENSP00000342070 | ENSP00000345344 | cathepsin B; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis | cathepsin L1; Important for the overall degradation of proteins in lysosomes | 0.700 |
CTSB | CTSL2 | ENSP00000342070 | ENSP00000259470 | cathepsin B; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis | cathepsin L2; Cysteine protease. May have an important role in corneal physiology | 0.685 |
CTSC | CST7 | ENSP00000227266 | ENSP00000420384 | cathepsin C | cystatin F (leukocystatin); Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system | 0.628 |
CTSC | CTSL1 | ENSP00000227266 | ENSP00000345344 | cathepsin C | cathepsin L1; Important for the overall degradation of proteins in lysosomes | 0.672 |
CTSF | CTSS | ENSP00000310832 | ENSP00000357981 | cathepsin F; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis | cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N | 0.916 |
CTSF | HLA-DRB1 | ENSP00000310832 | ENSP00000353099 | cathepsin F; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis | major histocompatibility complex, class II, DR beta 1 | 0.900 |
CTSL1 | CST7 | ENSP00000345344 | ENSP00000420384 | cathepsin L1; Important for the overall degradation of proteins in lysosomes | cystatin F (leukocystatin); Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system | 0.665 |
CTSL1 | CTSB | ENSP00000345344 | ENSP00000342070 | cathepsin L1; Important for the overall degradation of proteins in lysosomes | cathepsin B; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis | 0.700 |
CTSL1 | CTSC | ENSP00000345344 | ENSP00000227266 | cathepsin L1; Important for the overall degradation of proteins in lysosomes | cathepsin C | 0.672 |
CTSL1 | CTSS | ENSP00000345344 | ENSP00000357981 | cathepsin L1; Important for the overall degradation of proteins in lysosomes | cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N | 0.905 |
CTSL1 | HLA-DRB1 | ENSP00000345344 | ENSP00000353099 | cathepsin L1; Important for the overall degradation of proteins in lysosomes | major histocompatibility complex, class II, DR beta 1 | 0.901 |
CTSL2 | CTSB | ENSP00000259470 | ENSP00000342070 | cathepsin L2; Cysteine protease. May have an important role in corneal physiology | cathepsin B; Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis | 0.685 |
CTSL2 | CTSS | ENSP00000259470 | ENSP00000357981 | cathepsin L2; Cysteine protease. May have an important role in corneal physiology | cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N | 0.905 |
CTSL2 | HLA-DRB1 | ENSP00000259470 | ENSP00000353099 | cathepsin L2; Cysteine protease. May have an important role in corneal physiology | major histocompatibility complex, class II, DR beta 1 | 0.900 |
CTSS | CST7 | ENSP00000357981 | ENSP00000420384 | cathepsin S; Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond- specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N | cystatin F (leukocystatin); Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system | 0.475 |