5 items (Homo sapiens) - STRING network view

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	NGFR	nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells (427 aa)
	NGF	nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival (241 aa)
	NTF3	neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons (270 aa)
	BDNF	brain-derived neurotrophic factor (329 aa)
	SORCS2	sortilin-related VPS10 domain containing receptor 2 (1159 aa)

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BDNF	NGF	ENSP00000414303	ENSP00000358525	brain-derived neurotrophic factor	nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival	0.913
BDNF	NGFR	ENSP00000414303	ENSP00000172229	brain-derived neurotrophic factor	nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells	0.996
BDNF	NTF3	ENSP00000414303	ENSP00000397297	brain-derived neurotrophic factor	neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons	0.996
BDNF	SORCS2	ENSP00000414303	ENSP00000422185	brain-derived neurotrophic factor	sortilin-related VPS10 domain containing receptor 2	0.615
NGF	BDNF	ENSP00000358525	ENSP00000414303	nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival	brain-derived neurotrophic factor	0.913
NGF	NGFR	ENSP00000358525	ENSP00000172229	nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival	nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells	0.999
NGF	NTF3	ENSP00000358525	ENSP00000397297	nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival	neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons	0.906
NGF	SORCS2	ENSP00000358525	ENSP00000422185	nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival	sortilin-related VPS10 domain containing receptor 2	0.634
NGFR	BDNF	ENSP00000172229	ENSP00000414303	nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells	brain-derived neurotrophic factor	0.996
NGFR	NGF	ENSP00000172229	ENSP00000358525	nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells	nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival	0.999
NGFR	NTF3	ENSP00000172229	ENSP00000397297	nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells	neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons	0.995
NGFR	SORCS2	ENSP00000172229	ENSP00000422185	nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells	sortilin-related VPS10 domain containing receptor 2	0.924
NTF3	BDNF	ENSP00000397297	ENSP00000414303	neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons	brain-derived neurotrophic factor	0.996
NTF3	NGF	ENSP00000397297	ENSP00000358525	neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons	nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival	0.906
NTF3	NGFR	ENSP00000397297	ENSP00000172229	neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons	nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells	0.995
NTF3	SORCS2	ENSP00000397297	ENSP00000422185	neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons	sortilin-related VPS10 domain containing receptor 2	0.569
SORCS2	BDNF	ENSP00000422185	ENSP00000414303	sortilin-related VPS10 domain containing receptor 2	brain-derived neurotrophic factor	0.615
SORCS2	NGF	ENSP00000422185	ENSP00000358525	sortilin-related VPS10 domain containing receptor 2	nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival	0.634
SORCS2	NGFR	ENSP00000422185	ENSP00000172229	sortilin-related VPS10 domain containing receptor 2	nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells	0.924
SORCS2	NTF3	ENSP00000422185	ENSP00000397297	sortilin-related VPS10 domain containing receptor 2	neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons	0.569

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