node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BDNF | NGF | ENSP00000414303 | ENSP00000358525 | brain-derived neurotrophic factor | nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival | 0.913 |
BDNF | NGFR | ENSP00000414303 | ENSP00000172229 | brain-derived neurotrophic factor | nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells | 0.996 |
BDNF | NTF3 | ENSP00000414303 | ENSP00000397297 | brain-derived neurotrophic factor | neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons | 0.996 |
BDNF | SORCS2 | ENSP00000414303 | ENSP00000422185 | brain-derived neurotrophic factor | sortilin-related VPS10 domain containing receptor 2 | 0.615 |
NGF | BDNF | ENSP00000358525 | ENSP00000414303 | nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival | brain-derived neurotrophic factor | 0.913 |
NGF | NGFR | ENSP00000358525 | ENSP00000172229 | nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival | nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells | 0.999 |
NGF | NTF3 | ENSP00000358525 | ENSP00000397297 | nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival | neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons | 0.906 |
NGF | SORCS2 | ENSP00000358525 | ENSP00000422185 | nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival | sortilin-related VPS10 domain containing receptor 2 | 0.634 |
NGFR | BDNF | ENSP00000172229 | ENSP00000414303 | nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells | brain-derived neurotrophic factor | 0.996 |
NGFR | NGF | ENSP00000172229 | ENSP00000358525 | nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells | nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival | 0.999 |
NGFR | NTF3 | ENSP00000172229 | ENSP00000397297 | nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells | neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons | 0.995 |
NGFR | SORCS2 | ENSP00000172229 | ENSP00000422185 | nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells | sortilin-related VPS10 domain containing receptor 2 | 0.924 |
NTF3 | BDNF | ENSP00000397297 | ENSP00000414303 | neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons | brain-derived neurotrophic factor | 0.996 |
NTF3 | NGF | ENSP00000397297 | ENSP00000358525 | neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons | nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival | 0.906 |
NTF3 | NGFR | ENSP00000397297 | ENSP00000172229 | neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons | nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells | 0.995 |
NTF3 | SORCS2 | ENSP00000397297 | ENSP00000422185 | neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons | sortilin-related VPS10 domain containing receptor 2 | 0.569 |
SORCS2 | BDNF | ENSP00000422185 | ENSP00000414303 | sortilin-related VPS10 domain containing receptor 2 | brain-derived neurotrophic factor | 0.615 |
SORCS2 | NGF | ENSP00000422185 | ENSP00000358525 | sortilin-related VPS10 domain containing receptor 2 | nerve growth factor (beta polypeptide); Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival | 0.634 |
SORCS2 | NGFR | ENSP00000422185 | ENSP00000172229 | sortilin-related VPS10 domain containing receptor 2 | nerve growth factor receptor; Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells | 0.924 |
SORCS2 | NTF3 | ENSP00000422185 | ENSP00000397297 | sortilin-related VPS10 domain containing receptor 2 | neurotrophin 3; Seems to promote the survival of visceral and proprioceptive sensory neurons | 0.569 |