node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EIF2B1 | EIF2B2 | ENSP00000416250 | ENSP00000266126 | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP | 0.999 |
EIF2B1 | EIF2B4 | ENSP00000416250 | ENSP00000394869 | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP | 0.996 |
EIF2B1 | UBC | ENSP00000416250 | ENSP00000344818 | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP | ubiquitin C | 0.770 |
EIF2B2 | EIF2B1 | ENSP00000266126 | ENSP00000416250 | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP | 0.999 |
EIF2B2 | EIF2B4 | ENSP00000266126 | ENSP00000394869 | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP | 0.999 |
EIF2B2 | UBC | ENSP00000266126 | ENSP00000344818 | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP | ubiquitin C | 0.857 |
EIF2B4 | EIF2B1 | ENSP00000394869 | ENSP00000416250 | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP | eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP | 0.996 |
EIF2B4 | EIF2B2 | ENSP00000394869 | ENSP00000266126 | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP | 0.999 |
EIF2B4 | UBC | ENSP00000394869 | ENSP00000344818 | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa; Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP | ubiquitin C | 0.872 |
MRPL12 | NIT2 | ENSP00000333837 | ENSP00000377696 | mitochondrial ribosomal protein L12 | nitrilase family, member 2; Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha- ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle | 0.666 |
MRPL12 | RNASET2 | ENSP00000333837 | ENSP00000422846 | mitochondrial ribosomal protein L12 | ribonuclease T2; Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). Probably plays a role in cellular RNA catabolism | 0.858 |
MRPL12 | SUCLG2 | ENSP00000333837 | ENSP00000419325 | mitochondrial ribosomal protein L12 | succinate-CoA ligase, GDP-forming, beta subunit; Catalyzes the GTP-dependent ligation of succinate and CoA to form succinyl-CoA (By similarity) | 0.749 |
NDUFV1 | RNASET2 | ENSP00000322450 | ENSP00000422846 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) | ribonuclease T2; Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). Probably plays a role in cellular RNA catabolism | 0.644 |
NDUFV1 | UBC | ENSP00000322450 | ENSP00000344818 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity) | ubiquitin C | 0.620 |
NIT2 | MRPL12 | ENSP00000377696 | ENSP00000333837 | nitrilase family, member 2; Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha- ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle | mitochondrial ribosomal protein L12 | 0.666 |
NIT2 | RNASET2 | ENSP00000377696 | ENSP00000422846 | nitrilase family, member 2; Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha- ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle | ribonuclease T2; Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). Probably plays a role in cellular RNA catabolism | 0.907 |
NIT2 | UBC | ENSP00000377696 | ENSP00000344818 | nitrilase family, member 2; Has a omega-amidase activity. The role of omega-amidase is to remove potentially toxic intermediates by converting alpha- ketoglutaramate and alpha-ketosuccinamate to biologically useful alpha-ketoglutarate and oxaloacetate, respectively. Overexpression decreases the colony-forming capacity of cultured cells by arresting cells in the G2 phase of the cell cycle | ubiquitin C | 0.675 |
PRDX3 | RNASET2 | ENSP00000298510 | ENSP00000422846 | peroxiredoxin 3; Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol | ribonuclease T2; Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). Probably plays a role in cellular RNA catabolism | 0.662 |
PRDX3 | UBC | ENSP00000298510 | ENSP00000344818 | peroxiredoxin 3; Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol | ubiquitin C | 0.874 |
RNASET2 | MRPL12 | ENSP00000422846 | ENSP00000333837 | ribonuclease T2; Has ribonuclease activity, with higher activity at acidic pH. Probably is involved in lysosomal degradation of ribosomal RNA (By similarity). Probably plays a role in cellular RNA catabolism | mitochondrial ribosomal protein L12 | 0.858 |