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DCLK1 | doublecortin-like kinase 1; Probable kinase that may be involved in a calcium- signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system (729 aa) | |||
GIF | gastric intrinsic factor (vitamin B synthesis); Promotes absorption of the essential vitamin cobalamin (Cbl) in the ileum. After interaction with CUBN, the GIF-cobalamin complex is internalized via receptor-mediated endocytosis (417 aa) | |||
TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family); Vitamin B12-binding protein. Transports cobalamin into cells (433 aa) | |||
CCNE1 | cyclin E1; Essential for the control of the cell cycle at the G1/S (start) transition (410 aa) | |||
NID1 | nidogen 1; Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell- extracellular matrix interactions (1247 aa) | |||
TAPBPL | TAP binding protein-like (468 aa) | |||
BCAM | basal cell adhesion molecule (Lutheran blood group); Laminin alpha-5 receptor. May mediate intracellular signaling (628 aa) | |||
PDZD2 | PDZ domain containing 2 (2839 aa) | |||
CCNE2 | cyclin E2; Essential for the control of the cell cycle at the late G1 and early S phase (404 aa) | |||
EVX2 | even-skipped homeobox 2 (476 aa) | |||
IGSF9B | immunoglobulin superfamily, member 9B (1349 aa) | |||
E2F1 | E2F transcription factor 1; Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5’-TTTC[CG]CGC- 3’ found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F1 binds preferentially RB1 in a cell-cycle dependent manner. It can mediate both cell proliferation and TP53/p53-dependent apoptosis (437 aa) | |||
DLL1 | delta-like 1 (Drosophila); Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor (723 aa) | |||
SLAMF7 | SLAM family member 7; Isoform 1 mediates NK cell activation through a SH2D1A- independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion (335 aa) | |||
NEURL | neuralized homolog (Drosophila); May function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1, thereby regulating the Notch pathway (By similarity) (574 aa) | |||
NEURL1B | neuralized homolog 1B (Drosophila); E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands (555 aa) | |||
INADL | InaD-like (Drosophila) (1801 aa) | |||
LRIT1 | leucine-rich repeat, immunoglobulin-like and transmembrane domains 1; Possible role in phototransduction (623 aa) | |||
DLG5 | discs, large homolog 5 (Drosophila) (1919 aa) | |||
LYZL2 | lysozyme-like 2 (194 aa) | |||
LYZL1 | lysozyme-like 1 (194 aa) | |||
CASK | calcium/calmodulin-dependent serine protein kinase (MAGUK family) (921 aa) | |||
LRIT3 | leucine-rich repeat, immunoglobulin-like and transmembrane domains 3; Might facilitate FGFR1 exit from the endoplasmic reticulum to the Golgi (634 aa) | |||
IGSF11 | immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth (431 aa) | |||
EVX1 | even-skipped homeobox 1; May play a role in the specification of neuronal cell types (407 aa) | |||
EYS | eyes shut homolog (Drosophila) (3144 aa) |