node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADORA2A | ADORA2B | ENSP00000336630 | ENSP00000304501 | adenosine A2a receptor; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase | adenosine A2b receptor; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase | 0.903 |
ADORA2B | ADORA2A | ENSP00000304501 | ENSP00000336630 | adenosine A2b receptor; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase | adenosine A2a receptor; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase | 0.903 |
CSF2RA | CSF2RB | ENSP00000394227 | ENSP00000384053 | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor | 0.998 |
CSF2RA | SFTPB | ENSP00000394227 | ENSP00000377409 | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | surfactant protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter | 0.680 |
CSF2RA | SFTPC | ENSP00000394227 | ENSP00000316152 | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | surfactant protein C; Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces | 0.656 |
CSF2RB | CSF2RA | ENSP00000384053 | ENSP00000394227 | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | 0.998 |
CSF2RB | SFTPB | ENSP00000384053 | ENSP00000377409 | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor | surfactant protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter | 0.439 |
DMBT1 | SFTPA1 | ENSP00000357905 | ENSP00000397082 | deleted in malignant brain tumors 1 | surfactant protein A1 | 0.652 |
DMBT1 | SFTPD | ENSP00000357905 | ENSP00000361366 | deleted in malignant brain tumors 1 | surfactant protein D; Contributes to the lung’s defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties | 0.989 |
GATA6 | SFTPB | ENSP00000269216 | ENSP00000377409 | GATA binding protein 6; Transcriptional activator that regulates SEMA3C and PLXNA2. Thought to be important for regulating terminal differentiation and/or proliferation | surfactant protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter | 0.469 |
GATA6 | SFTPC | ENSP00000269216 | ENSP00000316152 | GATA binding protein 6; Transcriptional activator that regulates SEMA3C and PLXNA2. Thought to be important for regulating terminal differentiation and/or proliferation | surfactant protein C; Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces | 0.507 |
SFTPA1 | DMBT1 | ENSP00000397082 | ENSP00000357905 | surfactant protein A1 | deleted in malignant brain tumors 1 | 0.652 |
SFTPA1 | SFTPA2 | ENSP00000397082 | ENSP00000361400 | surfactant protein A1 | surfactant protein A2 | 0.956 |
SFTPA1 | SFTPB | ENSP00000397082 | ENSP00000377409 | surfactant protein A1 | surfactant protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter | 0.875 |
SFTPA1 | SFTPC | ENSP00000397082 | ENSP00000316152 | surfactant protein A1 | surfactant protein C; Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces | 0.879 |
SFTPA1 | SFTPD | ENSP00000397082 | ENSP00000361366 | surfactant protein A1 | surfactant protein D; Contributes to the lung’s defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties | 0.665 |
SFTPA2 | SFTPA1 | ENSP00000361400 | ENSP00000397082 | surfactant protein A2 | surfactant protein A1 | 0.956 |
SFTPA2 | SFTPB | ENSP00000361400 | ENSP00000377409 | surfactant protein A2 | surfactant protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter | 0.827 |
SFTPA2 | SFTPC | ENSP00000361400 | ENSP00000316152 | surfactant protein A2 | surfactant protein C; Pulmonary surfactant associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces | 0.783 |
SFTPB | CSF2RA | ENSP00000377409 | ENSP00000394227 | surfactant protein B; Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air- liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | 0.680 |