Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BYSL | DHX37 | ENSP00000230340 | ENSP00000311135 | bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos | DEAH (Asp-Glu-Ala-His) box polypeptide 37 | 0.991 |
BYSL | PAK1IP1 | ENSP00000230340 | ENSP00000368887 | bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos | PAK1 interacting protein 1; Negatively regulates the PAK1 kinase. PAK1 is a member of the PAK kinase family, which have been shown to play a positive role in the regulation of signaling pathways involving MAPK8 and RELA. PAK1 exists as an inactive homodimer, which is activated by binding of small GTPases such as CDC42 to an N-terminal regulatory domain. PAK1IP1 also binds to the N-terminus of PAK1, and inhibits the specific activation of PAK1 by CDC42 | 0.461 |
BYSL | YTHDC2 | ENSP00000230340 | ENSP00000161863 | bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos | YTH domain containing 2 | 0.460 |
CTU1 | KIAA1456 | ENSP00000390011 | ENSP00000432695 | cytosolic thiouridylase subunit 1 homolog (S. pombe); Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position | KIAA1456 | 0.465 |
DHX37 | BYSL | ENSP00000311135 | ENSP00000230340 | DEAH (Asp-Glu-Ala-His) box polypeptide 37 | bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos | 0.991 |
DHX37 | ENSG00000268412 | ENSP00000311135 | ENSP00000472299 | DEAH (Asp-Glu-Ala-His) box polypeptide 37 | Uncharacterized protein | 0.573 |
DHX37 | TRMT112 | ENSP00000311135 | ENSP00000438349 | DEAH (Asp-Glu-Ala-His) box polypeptide 37 | tRNA methyltransferase 11-2 homolog (S. cerevisiae); Participates both in methylation of protein and tRNA species. The heterodimer with HEMK2/N6AMT1 catalyzes N5- methylation of ETF1 on ’Gln-185’, using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species | 0.573 |
DHX37 | YTHDC2 | ENSP00000311135 | ENSP00000161863 | DEAH (Asp-Glu-Ala-His) box polypeptide 37 | YTH domain containing 2 | 0.551 |
ENSG00000268412 | DHX37 | ENSP00000472299 | ENSP00000311135 | Uncharacterized protein | DEAH (Asp-Glu-Ala-His) box polypeptide 37 | 0.573 |
ENSG00000268412 | HEMK1 | ENSP00000472299 | ENSP00000232854 | Uncharacterized protein | HemK methyltransferase family member 1; N5-glutamine methyltransferase responsible for the methylation of the GGQ triplet of the mitochondrial translation release factor MTRF1L | 0.631 |
ENSG00000268412 | KIAA1456 | ENSP00000472299 | ENSP00000432695 | Uncharacterized protein | KIAA1456 | 0.881 |
ENSG00000268412 | N6AMT1 | ENSP00000472299 | ENSP00000303584 | Uncharacterized protein | N-6 adenine-specific DNA methyltransferase 1 (putative); Heterodimeric methyltransferase that catalyzes N5- methylation of ETF1 on ’Gln-185’, using S-adenosyl L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid | 0.954 |
HEMK1 | ENSG00000268412 | ENSP00000232854 | ENSP00000472299 | HemK methyltransferase family member 1; N5-glutamine methyltransferase responsible for the methylation of the GGQ triplet of the mitochondrial translation release factor MTRF1L | Uncharacterized protein | 0.631 |
HEMK1 | TRMT112 | ENSP00000232854 | ENSP00000438349 | HemK methyltransferase family member 1; N5-glutamine methyltransferase responsible for the methylation of the GGQ triplet of the mitochondrial translation release factor MTRF1L | tRNA methyltransferase 11-2 homolog (S. cerevisiae); Participates both in methylation of protein and tRNA species. The heterodimer with HEMK2/N6AMT1 catalyzes N5- methylation of ETF1 on ’Gln-185’, using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species | 0.639 |
KIAA1456 | CTU1 | ENSP00000432695 | ENSP00000390011 | KIAA1456 | cytosolic thiouridylase subunit 1 homolog (S. pombe); Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position | 0.465 |
KIAA1456 | ENSG00000268412 | ENSP00000432695 | ENSP00000472299 | KIAA1456 | Uncharacterized protein | 0.881 |
KIAA1456 | N6AMT1 | ENSP00000432695 | ENSP00000303584 | KIAA1456 | N-6 adenine-specific DNA methyltransferase 1 (putative); Heterodimeric methyltransferase that catalyzes N5- methylation of ETF1 on ’Gln-185’, using S-adenosyl L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid | 0.544 |
KIAA1456 | TRMT112 | ENSP00000432695 | ENSP00000438349 | KIAA1456 | tRNA methyltransferase 11-2 homolog (S. cerevisiae); Participates both in methylation of protein and tRNA species. The heterodimer with HEMK2/N6AMT1 catalyzes N5- methylation of ETF1 on ’Gln-185’, using S-adenosyl L-methionine as methyl donor. The heterodimer with ALKBH8 catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA species | 0.881 |
MCM5 | RRM1 | ENSP00000216122 | ENSP00000300738 | minichromosome maintenance complex component 5; Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for ’once per cell cycle’ DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute dif [...] | ribonucleotide reductase M1; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) | 0.972 |
N6AMT1 | ENSG00000268412 | ENSP00000303584 | ENSP00000472299 | N-6 adenine-specific DNA methyltransferase 1 (putative); Heterodimeric methyltransferase that catalyzes N5- methylation of ETF1 on ’Gln-185’, using S-adenosyl L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid | Uncharacterized protein | 0.954 |
page 1 of 2