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SLC30A3 | solute carrier family 30 (zinc transporter), member 3; Involved in accumulation of zinc in synaptic vesicles (By similarity) (388 aa) | |||
SLC30A4 | solute carrier family 30 (zinc transporter), member 4; Probably involved in zinc transport out of the cytoplasm, maybe by sequestration into an intracellular compartment (429 aa) | |||
CD33 | CD33 molecule; Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro) (364 aa) | |||
DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 (793 aa) | |||
SLC39A3 | solute carrier family 39 (zinc transporter), member 3; Acts as a zinc-influx transporter (Potential) (314 aa) | |||
SLC39A2 | solute carrier family 39 (zinc transporter), member 2; Mediates zinc uptake. Zinc uptake may be mediated by a Zn(2+)-HCO(3)(-) symport mechanism and can function in the presence of albumin. May also transport other divalent cations. May be important in contact inhibition of normal epithelial cells and loss of its expression may play a role in tumorigenesis (309 aa) | |||
SLC39A1 | solute carrier family 39 (zinc transporter), member 1; Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells (324 aa) | |||
SLC30A7 | solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity) (376 aa) | |||
SPN | sialophorin; One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity). During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response [...] (400 aa) | |||
SLC30A10 | solute carrier family 30, member 10; May be involved in zinc transport out of the cell, being a zinc-efflux transporter (By similarity) (485 aa) | |||
SLC30A1 | solute carrier family 30 (zinc transporter), member 1; May be involved in zinc transport out of the cell (507 aa) | |||
C10orf35 | chromosome 10 open reading frame 35 (121 aa) | |||
SLC30A2 | solute carrier family 30 (zinc transporter), member 2 (372 aa) | |||
SLC30A6 | solute carrier family 30 (zinc transporter), member 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment (By similarity) (501 aa) | |||
SLC30A5 | solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP (765 aa) | |||
SLC30A8 | solute carrier family 30 (zinc transporter), member 8; Facilitates the accumulation of zinc from the cytoplasm into intracellular vesicles, being a zinc-efflux transporter. May be a major component for providing zinc to insulin maturation and/or storage processes in insulin-secreting pancreatic beta- cells (369 aa) | |||
SLC39A11 | solute carrier family 39 (metal ion transporter), member 11; May act as a zinc-influx transporter (By similarity) (342 aa) | |||
ENSG00000267001 | Uncharacterized protein (105 aa) |