node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FTCD | MTHFD1 | ENSP00000291670 | ENSP00000450560 | formiminotransferase cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.986 |
FTCD | MTHFD1L | ENSP00000291670 | ENSP00000356290 | formiminotransferase cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2 (By similarity) | 0.987 |
FTCD | MTHFD2 | ENSP00000291670 | ENSP00000377617 | formiminotransferase cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.960 |
FTCD | MTHFD2L | ENSP00000291670 | ENSP00000379108 | formiminotransferase cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.961 |
FTCD | ST20-MTHFS | ENSP00000291670 | ENSP00000455643 | formiminotransferase cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool | ST20-MTHFS protein | 0.930 |
FTCD | bA251O17.4 | ENSP00000291670 | ENSP00000316590 | formiminotransferase cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool | Uncharacterized protein | 0.768 |
MTHFD1 | FTCD | ENSP00000450560 | ENSP00000291670 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | formiminotransferase cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool | 0.986 |
MTHFD1 | MTHFD1L | ENSP00000450560 | ENSP00000356290 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2 (By similarity) | 0.977 |
MTHFD1 | MTHFD2 | ENSP00000450560 | ENSP00000377617 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.959 |
MTHFD1 | MTHFD2L | ENSP00000450560 | ENSP00000379108 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.956 |
MTHFD1 | ST20-MTHFS | ENSP00000450560 | ENSP00000455643 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | ST20-MTHFS protein | 0.986 |
MTHFD1 | bA251O17.4 | ENSP00000450560 | ENSP00000316590 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | Uncharacterized protein | 0.561 |
MTHFD1L | FTCD | ENSP00000356290 | ENSP00000291670 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2 (By similarity) | formiminotransferase cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool | 0.987 |
MTHFD1L | MTHFD1 | ENSP00000356290 | ENSP00000450560 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2 (By similarity) | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.977 |
MTHFD1L | MTHFD2 | ENSP00000356290 | ENSP00000377617 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2 (By similarity) | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.967 |
MTHFD1L | MTHFD2L | ENSP00000356290 | ENSP00000379108 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2 (By similarity) | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | 0.963 |
MTHFD1L | ST20-MTHFS | ENSP00000356290 | ENSP00000455643 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2 (By similarity) | ST20-MTHFS protein | 0.795 |
MTHFD1L | bA251O17.4 | ENSP00000356290 | ENSP00000316590 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like; May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2 (By similarity) | Uncharacterized protein | 0.551 |
MTHFD2 | FTCD | ENSP00000377617 | ENSP00000291670 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | formiminotransferase cyclodeaminase; Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool | 0.960 |
MTHFD2 | MTHFD1 | ENSP00000377617 | ENSP00000450560 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 0.959 |