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STRINGSTRING
ENSG00000261130 ENSG00000261130 TOMM20L TOMM20L TOMM40 TOMM40 ACLY ACLY TOMM22 TOMM22 TOMM40L TOMM40L TOMM20 TOMM20 SLC25A21 SLC25A21 RTN4 RTN4 RTN2 RTN2 RTN3 RTN3 RTN1 RTN1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
TOMM22translocase of outer mitochondrial membrane 22 homolog (yeast); Central receptor component of the translocase of the outer membrane of mitochondria (TOM complex) responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with the peripheral receptor TOM20 functions as the transit peptide receptor and facilitates the movement of preproteins into the translocation pore (142 aa)
RTN2reticulon 2 (545 aa)
TOMM40translocase of outer mitochondrial membrane 40 homolog (yeast); Channel-forming protein essential for import of protein precursors into mitochondria (By similarity) (361 aa)
ACLYATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine (1101 aa)
RTN1reticulon 1; May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells (776 aa)
SLC25A21solute carrier family 25 (mitochondrial oxoadipate carrier), member 21; Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate (299 aa)
RTN4reticulon 4 (1192 aa)
RTN3reticulon 3 (1013 aa)
TOMM20Ltranslocase of outer mitochondrial membrane 20 homolog (yeast)-like (152 aa)
TOMM20translocase of outer mitochondrial membrane 20 homolog (yeast); Central component of the receptor complex responsible for the recognition and translocation of cytosolically synthesized mitochondrial preproteins. Together with TOM22 functions as the transit peptide receptor at the surface of the mitochondrion outer membrane and facilitates the movement of preproteins into the TOM40 translocation pore (By similarity) (145 aa)
TOMM40Ltranslocase of outer mitochondrial membrane 40 homolog (yeast)-like; Potential channel-forming protein implicated in import of protein precursors into mitochondria (By similarity) (308 aa)
ENSG00000261130Uncharacterized protein (120 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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