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VAMP3 | vesicle-associated membrane protein 3; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network (100 aa) | |||
SNAP29 | synaptosomal-associated protein, 29kDa; SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Probably involved in multiple membrane trafficking steps (258 aa) | |||
YKT6 | YKT6 v-SNARE homolog (S. cerevisiae); Vesicular soluble NSF attachment protein receptor (v- SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity (198 aa) | |||
GOSR1 | golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide- sensitive factor) attachment protein receptor. May play a protective role against hydrogen peroxide induced cytotoxicity under glutathione depleted conditions in neuronal cells by regulating the intracellular ROS levels via inhibition of p38 MAPK (MAPK11, MAPK12, MAPK13 and MAPK14). Participates in docking and fusion stage of ER to cis-Golgi transport. Plays an impor [...] (250 aa) | |||
SNAP23 | synaptosomal-associated protein, 23kDa; Essential component of the high affinity receptor for the general membrane fusion machinery and an important regulator of transport vesicle docking and fusion (211 aa) | |||
SNAP25 | synaptosomal-associated protein, 25kDa (206 aa) | |||
STX6 | syntaxin 6; Involved in intracellular vesicle trafficking (255 aa) | |||
VAMP7 | vesicle-associated membrane protein 7; Involved in the targeting and/or fusion of transport vesicles to their target membrane during transport of proteins from the early endosome to the lysosome. Required for heterotypic fusion of late endosomes with lysosomes and homotypic lysosomal fusion. Required for calcium regulated lysosomal exocytosis. Involved in the export of chylomicrons from the endoplasmic reticulum to the cis Golgi. Required for exocytosis of mediators during eosinophil and neutrophil degranulation, and target cell killing by natural killer cells. Required for focal exocy [...] (260 aa) | |||
NAPA | N-ethylmaleimide-sensitive factor attachment protein, alpha; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (295 aa) | |||
VAMP8 | vesicle-associated membrane protein 8; SNAREs, Soluble N-ethylmaleimide-sensitive factor- attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. VAMP8 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Also required for dense-granule secretion in platelets. Plays also a role in regulated enzyme secretion in pancreatic acinar cells [...] (100 aa) | |||
SEC22C | SEC22 vesicle trafficking protein homolog C (S. cerevisiae); May be involved in vesicle transport between the ER and the Golgi complex (303 aa) | |||
STX5 | syntaxin 5; Mediates endoplasmic reticulum to Golgi transport (By similarity) (355 aa) | |||
STX8 | syntaxin 8; Vesicle trafficking protein that functions in the early secretory pathway, possibly by mediating retrograde transport from cis-Golgi membranes to the ER (236 aa) | |||
VAMP5 | vesicle-associated membrane protein 5; May participate in trafficking events that are associated with myogenesis, such as myoblast fusion and/or GLUT4 trafficking (116 aa) | |||
SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae); May be involved in vesicle transport between the ER and the Golgi complex (By similarity) (307 aa) | |||
VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2); Involved in the targeting and/or fusion of transport vesicles to their target membrane (116 aa) | |||
SNAP47 | synaptosomal-associated protein, 47kDa (464 aa) | |||
VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae); May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network (570 aa) | |||
NAPB | N-ethylmaleimide-sensitive factor attachment protein, beta; Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (By similarity) (298 aa) | |||
VTI1A | vesicle transport through interaction with t-SNAREs homolog 1A (yeast); V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. Involved in vesicular transport from the late endosomes to the trans-Golgi network. Along with VAMP7, involved in an non- conventional RAB1-dependent traffic route to the cell surface used by KCNIP1 and KCND2. May be involved in increased cytokine secretion associated with [...] (217 aa) | |||
VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1); Involved in the targeting and/or fusion of transport vesicles to their target membrane (118 aa) | |||
SCFD1 | sec1 family domain containing 1; Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi (By similarity) (642 aa) | |||
VTI1B | vesicle transport through interaction with t-SNAREs homolog 1B (yeast); V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence (232 aa) | |||
ENSG00000254995 | STX16-NPEPL1 readthrough (non-protein coding) (382 aa) | |||
ENSG00000263620 | Uncharacterized protein (121 aa) | |||
STX10 | syntaxin 10; SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network (249 aa) |