node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALB | APOA2 | ENSP00000295897 | ENSP00000356969 | albumin | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | 0.522 |
ALB | APOB | ENSP00000295897 | ENSP00000233242 | albumin | apolipoprotein B (including Ag(x) antigen) | 0.815 |
ALB | APOC2 | ENSP00000295897 | ENSP00000466775 | albumin | apolipoprotein C-II; Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly | 0.579 |
ALB | APOE | ENSP00000295897 | ENSP00000252486 | albumin | apolipoprotein E; Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues | 0.918 |
APC2 | APOC2 | ENSP00000233607 | ENSP00000466775 | adenomatosis polyposis coli 2; Promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. May function in Wnt signaling | apolipoprotein C-II; Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly | 0.569 |
APOA2 | ALB | ENSP00000356969 | ENSP00000295897 | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | albumin | 0.522 |
APOA2 | APOB | ENSP00000356969 | ENSP00000233242 | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | apolipoprotein B (including Ag(x) antigen) | 0.993 |
APOA2 | APOC2 | ENSP00000356969 | ENSP00000466775 | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | apolipoprotein C-II; Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly | 0.916 |
APOA2 | APOE | ENSP00000356969 | ENSP00000252486 | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | apolipoprotein E; Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues | 0.991 |
APOB | ALB | ENSP00000233242 | ENSP00000295897 | apolipoprotein B (including Ag(x) antigen) | albumin | 0.815 |
APOB | APOA2 | ENSP00000233242 | ENSP00000356969 | apolipoprotein B (including Ag(x) antigen) | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | 0.993 |
APOB | APOC2 | ENSP00000233242 | ENSP00000466775 | apolipoprotein B (including Ag(x) antigen) | apolipoprotein C-II; Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly | 0.920 |
APOB | APOE | ENSP00000233242 | ENSP00000252486 | apolipoprotein B (including Ag(x) antigen) | apolipoprotein E; Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues | 0.997 |
APOC2 | ALB | ENSP00000466775 | ENSP00000295897 | apolipoprotein C-II; Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly | albumin | 0.579 |
APOC2 | APC2 | ENSP00000466775 | ENSP00000233607 | apolipoprotein C-II; Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly | adenomatosis polyposis coli 2; Promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. May function in Wnt signaling | 0.569 |
APOC2 | APOA2 | ENSP00000466775 | ENSP00000356969 | apolipoprotein C-II; Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | 0.916 |
APOC2 | APOB | ENSP00000466775 | ENSP00000233242 | apolipoprotein C-II; Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly | apolipoprotein B (including Ag(x) antigen) | 0.920 |
APOC2 | APOE | ENSP00000466775 | ENSP00000252486 | apolipoprotein C-II; Component of the very low density lipoprotein (VLDL) fraction in plasma, and is an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly | apolipoprotein E; Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues | 0.983 |
APOE | ALB | ENSP00000252486 | ENSP00000295897 | apolipoprotein E; Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues | albumin | 0.918 |
APOE | APOA2 | ENSP00000252486 | ENSP00000356969 | apolipoprotein E; Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues | apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism | 0.991 |