Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
ISL1 ISL1 SEC11C SEC11C RPL35 RPL35 RPL18A RPL18A RPS16 RPS16 RPL8 RPL8 RPL30 RPL30 RPN2 RPN2 SSR1 SSR1 RPL6 RPL6 RPL37 RPL37 RPL38 RPL38 RPS14 RPS14 SSR3 SSR3 RPS5 RPS5 RPL3L RPL3L RPS12 RPS12 RPL19 RPL19 RPS23 RPS23 SRP14 SRP14 RPL29 RPL29 RPLP2 RPLP2 RPS11 RPS11 SEC61B SEC61B SRP68 SRP68 SRP9 SRP9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
RPS5ribosomal protein S5 (204 aa)
RPL6ribosomal protein L6; Specifically binds to domain C of the Tax-responsive enhancer element in the long terminal repeat of HTLV-I (288 aa)
RPL18Aribosomal protein L18a (176 aa)
SEC61BSec61 beta subunit; Necessary for protein translocation in the endoplasmic reticulum (96 aa)
RPL19ribosomal protein L19 (196 aa)
RPS12ribosomal protein S12 (132 aa)
ISL1ISL LIM homeobox 1; Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1 (By similarity) (349 aa)
RPN2ribophorin II; Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains (631 aa)
SSR1signal sequence receptor, alpha (286 aa)
RPS16ribosomal protein S16 (146 aa)
RPL35ribosomal protein L35 (123 aa)
RPL8ribosomal protein L8 (257 aa)
SSR3signal sequence receptor, gamma (translocon-associated protein gamma); TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins (185 aa)
SRP14signal recognition particle 14kDa (homologous Alu RNA binding protein); Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding (136 aa)
RPL3Lribosomal protein L3-like (407 aa)
RPS11ribosomal protein S11 (158 aa)
RPL37ribosomal protein L37; Binds to the 23S rRNA (By similarity) (97 aa)
RPL30ribosomal protein L30 (115 aa)
RPL29ribosomal protein L29 (159 aa)
RPS23ribosomal protein S23 (143 aa)
SRP9signal recognition particle 9kDa; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding (86 aa)
RPL38ribosomal protein L38 (70 aa)
RPS14ribosomal protein S14 (151 aa)
SRP68signal recognition particle 68kDa; Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP68 binds the 7S RNA, SRP72 binds to this complex subsequently. This ribonucleoprotein complex might interact directly with the docking protein in the ER membrane and possibly participate in the elongation arrest function (627 aa)
RPLP2ribosomal protein, large, P2; Plays an important role in the elongation step of protein synthesis (115 aa)
SEC11CSEC11 homolog C (S. cerevisiae); Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum (By similarity) (192 aa)
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: medium (57%)