OSBPL7 protein (Homo sapiens) - STRING network view

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OSBPL7

oxysterol binding protein-like 7 (842 aa)

Predicted Functional Partners:

PRKD1

0.613

PRKD2

0.613

PRKD3

0.613

PLEK

0.606

VAPB

0.606

VAPA

0.602

MOSPD3

0.602

RRAS

0.537

ZNF567

0.419

OSBPL8

0.415

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MOSPD3	OSBPL7	ENSP00000223054	ENSP00000007414	motile sperm domain containing 3	oxysterol binding protein-like 7	0.602
OSBPL7	MOSPD3	ENSP00000007414	ENSP00000223054	oxysterol binding protein-like 7	motile sperm domain containing 3	0.602
OSBPL7	OSBPL8	ENSP00000007414	ENSP00000261183	oxysterol binding protein-like 7	oxysterol binding protein-like 8	0.415
OSBPL7	PLEK	ENSP00000007414	ENSP00000234313	oxysterol binding protein-like 7	pleckstrin; Major protein kinase C substrate of platelets	0.606
OSBPL7	PRKD1	ENSP00000007414	ENSP00000333568	oxysterol binding protein-like 7	protein kinase D1; Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and trafficking, cell survival through NF-kappa-B activation, cell migration, cell differentiation by mediating HDAC7 nuclear export, cell proliferation via MAPK1/3 (ERK1/2) signaling, and plays a role in cardiac hypertrophy, VEGFA-induced angiogenesis, genotoxic-induced apoptosis and flagellin-stimulated inflammatory response. Phosphoryl [...]	0.613
OSBPL7	PRKD2	ENSP00000007414	ENSP00000291281	oxysterol binding protein-like 7	protein kinase D2; Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of cell proliferation via MAPK1/3 (ERK1/2) signaling, oxidative stress- induced NF-kappa-B activation, inhibition of HDAC7 transcriptional repression, signaling downstream of T-cell antigen receptor (TCR) and cytokine production, and plays a role in Golgi membrane trafficking, angiogenesis, secretory granule release and cell adhesion. May potentiate mitogenesis induced by the neuropeptide bombes [...]	0.613
OSBPL7	PRKD3	ENSP00000007414	ENSP00000234179	oxysterol binding protein-like 7	protein kinase D3; Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity)	0.613
OSBPL7	RRAS	ENSP00000007414	ENSP00000246792	oxysterol binding protein-like 7	related RAS viral (r-ras) oncogene homolog; Regulates the organization of the actin cytoskeleton	0.537
OSBPL7	VAPA	ENSP00000007414	ENSP00000345656	oxysterol binding protein-like 7	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa; May play a role in vesicle trafficking	0.602
OSBPL7	VAPB	ENSP00000007414	ENSP00000417175	oxysterol binding protein-like 7	VAMP (vesicle-associated membrane protein)-associated protein B and C; Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation	0.606
OSBPL7	ZNF567	ENSP00000007414	ENSP00000353957	oxysterol binding protein-like 7	zinc finger protein 567; May be involved in transcriptional regulation	0.419
OSBPL8	OSBPL7	ENSP00000261183	ENSP00000007414	oxysterol binding protein-like 8	oxysterol binding protein-like 7	0.415
OSBPL8	PLEK	ENSP00000261183	ENSP00000234313	oxysterol binding protein-like 8	pleckstrin; Major protein kinase C substrate of platelets	0.560
PLEK	OSBPL7	ENSP00000234313	ENSP00000007414	pleckstrin; Major protein kinase C substrate of platelets	oxysterol binding protein-like 7	0.606
PLEK	OSBPL8	ENSP00000234313	ENSP00000261183	pleckstrin; Major protein kinase C substrate of platelets	oxysterol binding protein-like 8	0.560
PLEK	PRKD1	ENSP00000234313	ENSP00000333568	pleckstrin; Major protein kinase C substrate of platelets	protein kinase D1; Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and trafficking, cell survival through NF-kappa-B activation, cell migration, cell differentiation by mediating HDAC7 nuclear export, cell proliferation via MAPK1/3 (ERK1/2) signaling, and plays a role in cardiac hypertrophy, VEGFA-induced angiogenesis, genotoxic-induced apoptosis and flagellin-stimulated inflammatory response. Phosphoryl [...]	0.509
PLEK	PRKD2	ENSP00000234313	ENSP00000291281	pleckstrin; Major protein kinase C substrate of platelets	protein kinase D2; Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of cell proliferation via MAPK1/3 (ERK1/2) signaling, oxidative stress- induced NF-kappa-B activation, inhibition of HDAC7 transcriptional repression, signaling downstream of T-cell antigen receptor (TCR) and cytokine production, and plays a role in Golgi membrane trafficking, angiogenesis, secretory granule release and cell adhesion. May potentiate mitogenesis induced by the neuropeptide bombes [...]	0.410
PLEK	PRKD3	ENSP00000234313	ENSP00000234179	pleckstrin; Major protein kinase C substrate of platelets	protein kinase D3; Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity)	0.499
PRKD1	OSBPL7	ENSP00000333568	ENSP00000007414	protein kinase D1; Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and trafficking, cell survival through NF-kappa-B activation, cell migration, cell differentiation by mediating HDAC7 nuclear export, cell proliferation via MAPK1/3 (ERK1/2) signaling, and plays a role in cardiac hypertrophy, VEGFA-induced angiogenesis, genotoxic-induced apoptosis and flagellin-stimulated inflammatory response. Phosphoryl [...]	oxysterol binding protein-like 7	0.613
PRKD1	PLEK	ENSP00000333568	ENSP00000234313	protein kinase D1; Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and trafficking, cell survival through NF-kappa-B activation, cell migration, cell differentiation by mediating HDAC7 nuclear export, cell proliferation via MAPK1/3 (ERK1/2) signaling, and plays a role in cardiac hypertrophy, VEGFA-induced angiogenesis, genotoxic-induced apoptosis and flagellin-stimulated inflammatory response. Phosphoryl [...]	pleckstrin; Major protein kinase C substrate of platelets	0.509

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