| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CNBD2 | DYRK4 | ENSP00000340954 | ENSP00000010132 | cyclic nucleotide binding domain containing 2 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | 0.772 |
| DCAF7 | DYRK4 | ENSP00000308344 | ENSP00000010132 | DDB1 and CUL4 associated factor 7; Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4- DDB1 E3 ubiquitin-protein ligase complex | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | 0.846 |
| DCAF7 | YWHAZ | ENSP00000308344 | ENSP00000309503 | DDB1 and CUL4 associated factor 7; Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4- DDB1 E3 ubiquitin-protein ligase complex | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.489 |
| DYRK4 | CNBD2 | ENSP00000010132 | ENSP00000340954 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | cyclic nucleotide binding domain containing 2 | 0.772 |
| DYRK4 | DCAF7 | ENSP00000010132 | ENSP00000308344 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | DDB1 and CUL4 associated factor 7; Involved in craniofacial development. Acts upstream of the EDN1 pathway and is required for formation of the upper jaw equivalent, the palatoquadrate. The activity required for EDN1 pathway function differs between the first and second arches (By similarity). Associates with DIAPH1 and controls GLI1 transcriptional activity. Could be involved in normal and disease skin development. May function as a substrate receptor for CUL4- DDB1 E3 ubiquitin-protein ligase complex | 0.846 |
| DYRK4 | KATNA1 | ENSP00000010132 | ENSP00000335106 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | katanin p60 (ATPase containing) subunit A 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neurona [...] | 0.762 |
| DYRK4 | KATNAL1 | ENSP00000010132 | ENSP00000369989 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | katanin p60 subunit A-like 1; Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity) | 0.762 |
| DYRK4 | PRKAR1A | ENSP00000010132 | ENSP00000351410 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | protein kinase, cAMP-dependent, regulatory, type I, alpha; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells | 0.775 |
| DYRK4 | PRKAR1B | ENSP00000010132 | ENSP00000353415 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | protein kinase, cAMP-dependent, regulatory, type I, beta; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells | 0.775 |
| DYRK4 | PRKAR2A | ENSP00000010132 | ENSP00000265563 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | protein kinase, cAMP-dependent, regulatory, type II, alpha; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase | 0.775 |
| DYRK4 | PRKAR2B | ENSP00000010132 | ENSP00000265717 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | protein kinase, cAMP-dependent, regulatory, type II, beta; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase | 0.775 |
| DYRK4 | YWHAG | ENSP00000010132 | ENSP00000306330 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner | 0.725 |
| DYRK4 | YWHAZ | ENSP00000010132 | ENSP00000309503 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.728 |
| KATNA1 | DYRK4 | ENSP00000335106 | ENSP00000010132 | katanin p60 (ATPase containing) subunit A 1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neurona [...] | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | 0.762 |
| KATNAL1 | DYRK4 | ENSP00000369989 | ENSP00000010132 | katanin p60 subunit A-like 1; Regulates microtubule dynamics in Sertoli cells, a process that is essential for spermiogenesis and male fertility. Severs microtubules in an ATP-dependent manner, promoting rapid reorganization of cellular microtubule arrays (By similarity) | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | 0.762 |
| PRKAR1A | DYRK4 | ENSP00000351410 | ENSP00000010132 | protein kinase, cAMP-dependent, regulatory, type I, alpha; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | 0.775 |
| PRKAR1A | PRKAR1B | ENSP00000351410 | ENSP00000353415 | protein kinase, cAMP-dependent, regulatory, type I, alpha; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells | protein kinase, cAMP-dependent, regulatory, type I, beta; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells | 0.980 |
| PRKAR1A | PRKAR2A | ENSP00000351410 | ENSP00000265563 | protein kinase, cAMP-dependent, regulatory, type I, alpha; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells | protein kinase, cAMP-dependent, regulatory, type II, alpha; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase | 0.910 |
| PRKAR1A | PRKAR2B | ENSP00000351410 | ENSP00000265717 | protein kinase, cAMP-dependent, regulatory, type I, alpha; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells | protein kinase, cAMP-dependent, regulatory, type II, beta; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase | 0.911 |
| PRKAR1B | DYRK4 | ENSP00000353415 | ENSP00000010132 | protein kinase, cAMP-dependent, regulatory, type I, beta; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; Possible non-essential role in spermiogenesis (By similarity) | 0.775 |
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