node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C1orf173 | SLC45A4 | ENSP00000322609 | ENSP00000024061 | chromosome 1 open reading frame 173 | solute carrier family 45, member 4 | 0.580 |
C1orf173 | TTC23 | ENSP00000322609 | ENSP00000262074 | chromosome 1 open reading frame 173 | tetratricopeptide repeat domain 23 | 0.721 |
SLC17A5 | SLC35D2 | ENSP00000348019 | ENSP00000253270 | solute carrier family 17 (anion/sugar transporter), member 5; Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is required for normal CNS myelination. Mediates aspartate and glutamate membrane potential- dependent uptake into synaptic vesicles and synaptic-like microvesicles. Also functions as an electrogenic 2NO(3)(-)/H(+) cotransporter in the plasma membrane of salivary gland acinar cells, mediating the physiological nitrate efflux, 25% of the circulating nitrate ions is typically removed an [...] | solute carrier family 35, member D2; Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling | 0.438 |
SLC17A5 | SLC45A4 | ENSP00000348019 | ENSP00000024061 | solute carrier family 17 (anion/sugar transporter), member 5; Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is required for normal CNS myelination. Mediates aspartate and glutamate membrane potential- dependent uptake into synaptic vesicles and synaptic-like microvesicles. Also functions as an electrogenic 2NO(3)(-)/H(+) cotransporter in the plasma membrane of salivary gland acinar cells, mediating the physiological nitrate efflux, 25% of the circulating nitrate ions is typically removed an [...] | solute carrier family 45, member 4 | 0.513 |
SLC17A5 | SLC6A18 | ENSP00000348019 | ENSP00000323549 | solute carrier family 17 (anion/sugar transporter), member 5; Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is required for normal CNS myelination. Mediates aspartate and glutamate membrane potential- dependent uptake into synaptic vesicles and synaptic-like microvesicles. Also functions as an electrogenic 2NO(3)(-)/H(+) cotransporter in the plasma membrane of salivary gland acinar cells, mediating the physiological nitrate efflux, 25% of the circulating nitrate ions is typically removed an [...] | solute carrier family 6, member 18; Functions as a sodium and chloride-dependent neutral amino acid transporter (By similarity) | 0.488 |
SLC17A5 | SLC7A14 | ENSP00000348019 | ENSP00000231706 | solute carrier family 17 (anion/sugar transporter), member 5; Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is required for normal CNS myelination. Mediates aspartate and glutamate membrane potential- dependent uptake into synaptic vesicles and synaptic-like microvesicles. Also functions as an electrogenic 2NO(3)(-)/H(+) cotransporter in the plasma membrane of salivary gland acinar cells, mediating the physiological nitrate efflux, 25% of the circulating nitrate ions is typically removed an [...] | solute carrier family 7 (orphan transporter), member 14 | 0.422 |
SLC17A5 | SLC9A6 | ENSP00000348019 | ENSP00000359729 | solute carrier family 17 (anion/sugar transporter), member 5; Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is required for normal CNS myelination. Mediates aspartate and glutamate membrane potential- dependent uptake into synaptic vesicles and synaptic-like microvesicles. Also functions as an electrogenic 2NO(3)(-)/H(+) cotransporter in the plasma membrane of salivary gland acinar cells, mediating the physiological nitrate efflux, 25% of the circulating nitrate ions is typically removed an [...] | solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 | 0.413 |
SLC17A5 | SLCO5A1 | ENSP00000348019 | ENSP00000260126 | solute carrier family 17 (anion/sugar transporter), member 5; Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is required for normal CNS myelination. Mediates aspartate and glutamate membrane potential- dependent uptake into synaptic vesicles and synaptic-like microvesicles. Also functions as an electrogenic 2NO(3)(-)/H(+) cotransporter in the plasma membrane of salivary gland acinar cells, mediating the physiological nitrate efflux, 25% of the circulating nitrate ions is typically removed an [...] | solute carrier organic anion transporter family, member 5A1 | 0.451 |
SLC17A5 | SLCO6A1 | ENSP00000348019 | ENSP00000369135 | solute carrier family 17 (anion/sugar transporter), member 5; Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is required for normal CNS myelination. Mediates aspartate and glutamate membrane potential- dependent uptake into synaptic vesicles and synaptic-like microvesicles. Also functions as an electrogenic 2NO(3)(-)/H(+) cotransporter in the plasma membrane of salivary gland acinar cells, mediating the physiological nitrate efflux, 25% of the circulating nitrate ions is typically removed an [...] | solute carrier organic anion transporter family, member 6A1 | 0.487 |
SLC28A3 | SLC35D2 | ENSP00000365413 | ENSP00000253270 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 3; Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2-1 sodium/nucleoside ratio. Also able to transport gemcitabine, 3’-azido-3’-deoxythymidine (AZT), ribavirin and 3-deazauridine | solute carrier family 35, member D2; Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling | 0.432 |
SLC28A3 | SLC45A4 | ENSP00000365413 | ENSP00000024061 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 3; Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2-1 sodium/nucleoside ratio. Also able to transport gemcitabine, 3’-azido-3’-deoxythymidine (AZT), ribavirin and 3-deazauridine | solute carrier family 45, member 4 | 0.521 |
SLC28A3 | SLC6A18 | ENSP00000365413 | ENSP00000323549 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 3; Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2-1 sodium/nucleoside ratio. Also able to transport gemcitabine, 3’-azido-3’-deoxythymidine (AZT), ribavirin and 3-deazauridine | solute carrier family 6, member 18; Functions as a sodium and chloride-dependent neutral amino acid transporter (By similarity) | 0.466 |
SLC28A3 | SLC7A14 | ENSP00000365413 | ENSP00000231706 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 3; Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2-1 sodium/nucleoside ratio. Also able to transport gemcitabine, 3’-azido-3’-deoxythymidine (AZT), ribavirin and 3-deazauridine | solute carrier family 7 (orphan transporter), member 14 | 0.471 |
SLC28A3 | SLCO5A1 | ENSP00000365413 | ENSP00000260126 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 3; Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2-1 sodium/nucleoside ratio. Also able to transport gemcitabine, 3’-azido-3’-deoxythymidine (AZT), ribavirin and 3-deazauridine | solute carrier organic anion transporter family, member 5A1 | 0.468 |
SLC28A3 | SLCO6A1 | ENSP00000365413 | ENSP00000369135 | solute carrier family 28 (sodium-coupled nucleoside transporter), member 3; Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2-1 sodium/nucleoside ratio. Also able to transport gemcitabine, 3’-azido-3’-deoxythymidine (AZT), ribavirin and 3-deazauridine | solute carrier organic anion transporter family, member 6A1 | 0.457 |
SLC35D2 | SLC17A5 | ENSP00000253270 | ENSP00000348019 | solute carrier family 35, member D2; Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling | solute carrier family 17 (anion/sugar transporter), member 5; Transports glucuronic acid and free sialic acid out of the lysosome after it is cleaved from sialoglycoconjugates undergoing degradation, this is required for normal CNS myelination. Mediates aspartate and glutamate membrane potential- dependent uptake into synaptic vesicles and synaptic-like microvesicles. Also functions as an electrogenic 2NO(3)(-)/H(+) cotransporter in the plasma membrane of salivary gland acinar cells, mediating the physiological nitrate efflux, 25% of the circulating nitrate ions is typically removed an [...] | 0.438 |
SLC35D2 | SLC28A3 | ENSP00000253270 | ENSP00000365413 | solute carrier family 35, member D2; Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling | solute carrier family 28 (sodium-coupled nucleoside transporter), member 3; Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides. Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transport of both thymidine and inosine). Employs a 2-1 sodium/nucleoside ratio. Also able to transport gemcitabine, 3’-azido-3’-deoxythymidine (AZT), ribavirin and 3-deazauridine | 0.432 |
SLC35D2 | SLC45A4 | ENSP00000253270 | ENSP00000024061 | solute carrier family 35, member D2; Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling | solute carrier family 45, member 4 | 0.527 |
SLC35D2 | SLC6A18 | ENSP00000253270 | ENSP00000323549 | solute carrier family 35, member D2; Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling | solute carrier family 6, member 18; Functions as a sodium and chloride-dependent neutral amino acid transporter (By similarity) | 0.490 |
SLC35D2 | SLC7A14 | ENSP00000253270 | ENSP00000231706 | solute carrier family 35, member D2; Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling | solute carrier family 7 (orphan transporter), member 14 | 0.501 |