| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCDC22 | KIAA2022 | ENSP00000365401 | ENSP00000055682 | coiled-coil domain containing 22 | KIAA2022 | 0.581 |
| CCDC22 | NXF5 | ENSP00000365401 | ENSP00000426978 | coiled-coil domain containing 22 | nuclear RNA export factor 5 | 0.505 |
| CCDC22 | SHROOM4 | ENSP00000365401 | ENSP00000289292 | coiled-coil domain containing 22 | shroom family member 4; Probable regulator of cytoskeletal architecture that plays an important role in development. May regulate cellular and cytoskeletal architecture by modulating the spatial distribution of myosin II (By similarity) | 0.633 |
| CCDC22 | ZDHHC15 | ENSP00000365401 | ENSP00000362465 | coiled-coil domain containing 22 | zinc finger, DHHC-type containing 15; Palmitoyltransferase specific for GAP43 and DLG4/PSD95 (By similarity) | 0.475 |
| CRCP | KIAA2022 | ENSP00000378736 | ENSP00000055682 | CGRP receptor component; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- [...] | KIAA2022 | 0.540 |
| CRCP | POLD1 | ENSP00000378736 | ENSP00000406046 | CGRP receptor component; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- [...] | polymerase (DNA directed), delta 1, catalytic subunit; Possesses two enzymatic activities- DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3’- to 5’-direction. Required with its accessory proteins (proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) or activator 1) for leading strand synthesis. Also involved in completing Okazaki fragments initiated by the DNA polymerase alpha/primase complex | 0.540 |
| CRCP | POLE3 | ENSP00000378736 | ENSP00000363284 | CGRP receptor component; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- [...] | polymerase (DNA directed), epsilon 3, accessory subunit; Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1 | 0.908 |
| CRCP | POLE4 | ENSP00000378736 | ENSP00000420176 | CGRP receptor component; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- [...] | polymerase (DNA-directed), epsilon 4, accessory subunit; May play a role in allowing polymerase epsilon to carry out its replication and/or repair function | 0.900 |
| CRCP | REV3L | ENSP00000378736 | ENSP00000351697 | CGRP receptor component; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- [...] | REV3-like, polymerase (DNA directed), zeta, catalytic subunit; Interacts with MAD2L2 to form the error prone DNA polymerase zeta involved in translesion DNA synthesis | 0.900 |
| KIAA2022 | CCDC22 | ENSP00000055682 | ENSP00000365401 | KIAA2022 | coiled-coil domain containing 22 | 0.581 |
| KIAA2022 | CRCP | ENSP00000055682 | ENSP00000378736 | KIAA2022 | CGRP receptor component; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts induce type I interferon and NF- [...] | 0.540 |
| KIAA2022 | NXF5 | ENSP00000055682 | ENSP00000426978 | KIAA2022 | nuclear RNA export factor 5 | 0.581 |
| KIAA2022 | P2RY8 | ENSP00000055682 | ENSP00000370697 | KIAA2022 | purinergic receptor P2Y, G-protein coupled, 8; Probable receptor for purines coupled to G-proteins | 0.861 |
| KIAA2022 | POLD1 | ENSP00000055682 | ENSP00000406046 | KIAA2022 | polymerase (DNA directed), delta 1, catalytic subunit; Possesses two enzymatic activities- DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3’- to 5’-direction. Required with its accessory proteins (proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) or activator 1) for leading strand synthesis. Also involved in completing Okazaki fragments initiated by the DNA polymerase alpha/primase complex | 0.540 |
| KIAA2022 | POLE3 | ENSP00000055682 | ENSP00000363284 | KIAA2022 | polymerase (DNA directed), epsilon 3, accessory subunit; Forms a complex with DNA polymerase epsilon subunit CHRAC1 and binds naked DNA, which is then incorporated into chromatin, aided by the nucleosome-remodeling activity of ISWI/SNF2H and ACF1 | 0.540 |
| KIAA2022 | POLE4 | ENSP00000055682 | ENSP00000420176 | KIAA2022 | polymerase (DNA-directed), epsilon 4, accessory subunit; May play a role in allowing polymerase epsilon to carry out its replication and/or repair function | 0.540 |
| KIAA2022 | REV3L | ENSP00000055682 | ENSP00000351697 | KIAA2022 | REV3-like, polymerase (DNA directed), zeta, catalytic subunit; Interacts with MAD2L2 to form the error prone DNA polymerase zeta involved in translesion DNA synthesis | 0.540 |
| KIAA2022 | SHROOM4 | ENSP00000055682 | ENSP00000289292 | KIAA2022 | shroom family member 4; Probable regulator of cytoskeletal architecture that plays an important role in development. May regulate cellular and cytoskeletal architecture by modulating the spatial distribution of myosin II (By similarity) | 0.568 |
| KIAA2022 | ZDHHC15 | ENSP00000055682 | ENSP00000362465 | KIAA2022 | zinc finger, DHHC-type containing 15; Palmitoyltransferase specific for GAP43 and DLG4/PSD95 (By similarity) | 0.580 |
| NXF5 | CCDC22 | ENSP00000426978 | ENSP00000365401 | nuclear RNA export factor 5 | coiled-coil domain containing 22 | 0.505 |
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