node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CD209 | CEACAM1 | ENSP00000315477 | ENSP00000161559 | CD209 molecule | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.939 |
CD209 | LCK | ENSP00000315477 | ENSP00000337825 | CD209 molecule | lymphocyte-specific protein tyrosine kinase | 0.841 |
CD209 | ZAP70 | ENSP00000315477 | ENSP00000264972 | CD209 molecule | zeta-chain (TCR) associated protein kinase 70kDa; Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates motility, adhesion and cytokine expression of mature T-cells, as well as thymocyte development. Contributes also to the development and activation of primary B-lymphocytes. When antigen presenting cells (APC) activate T-cell receptor (TCR), a serie of phosphorylations lead to the recruitment of ZAP70 to the doubly phosphorylated TCR component CD247/CD3Z through ITAM motif at the plasma membrane. This recruitment serves to localization t [...] | 0.831 |
CEACAM1 | CD209 | ENSP00000161559 | ENSP00000315477 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | CD209 molecule | 0.939 |
CEACAM1 | CEACAM6 | ENSP00000161559 | ENSP00000199764 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.970 |
CEACAM1 | CEACAM8 | ENSP00000161559 | ENSP00000244336 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.970 |
CEACAM1 | CRH | ENSP00000161559 | ENSP00000276571 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | corticotropin releasing hormone; This hormone from hypothalamus regulates the release of corticotropin from pituitary gland | 0.823 |
CEACAM1 | FLNA | ENSP00000161559 | ENSP00000358866 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | filamin A, alpha; Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface- localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis | 0.951 |
CEACAM1 | LCK | ENSP00000161559 | ENSP00000337825 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | lymphocyte-specific protein tyrosine kinase | 0.834 |
CEACAM1 | PTPN11 | ENSP00000161559 | ENSP00000340944 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | protein tyrosine phosphatase, non-receptor type 11; Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity | 0.894 |
CEACAM1 | SOX9 | ENSP00000161559 | ENSP00000245479 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | SRY (sex determining region Y)-box 9; Plays an important role in the normal skeletal development. May regulate the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes | 0.866 |
CEACAM1 | VEGFA | ENSP00000161559 | ENSP00000361125 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | vascular endothelial growth factor A | 0.844 |
CEACAM1 | ZAP70 | ENSP00000161559 | ENSP00000264972 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | zeta-chain (TCR) associated protein kinase 70kDa; Tyrosine kinase that plays an essential role in regulation of the adaptive immune response. Regulates motility, adhesion and cytokine expression of mature T-cells, as well as thymocyte development. Contributes also to the development and activation of primary B-lymphocytes. When antigen presenting cells (APC) activate T-cell receptor (TCR), a serie of phosphorylations lead to the recruitment of ZAP70 to the doubly phosphorylated TCR component CD247/CD3Z through ITAM motif at the plasma membrane. This recruitment serves to localization t [...] | 0.836 |
CEACAM6 | CEACAM1 | ENSP00000199764 | ENSP00000161559 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.970 |
CEACAM6 | CEACAM8 | ENSP00000199764 | ENSP00000244336 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | carcinoembryonic antigen-related cell adhesion molecule 8 | 0.970 |
CEACAM8 | CEACAM1 | ENSP00000244336 | ENSP00000161559 | carcinoembryonic antigen-related cell adhesion molecule 8 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.970 |
CEACAM8 | CEACAM6 | ENSP00000244336 | ENSP00000199764 | carcinoembryonic antigen-related cell adhesion molecule 8 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.970 |
CRH | CEACAM1 | ENSP00000276571 | ENSP00000161559 | corticotropin releasing hormone; This hormone from hypothalamus regulates the release of corticotropin from pituitary gland | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.823 |
FLNA | CEACAM1 | ENSP00000358866 | ENSP00000161559 | filamin A, alpha; Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface- localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.951 |
FLNA | LCK | ENSP00000358866 | ENSP00000337825 | filamin A, alpha; Promotes orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton and serves as a scaffold for a wide range of cytoplasmic signaling proteins. Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate. Tethers cell surface- localized furin, modulates its rate of internalization and directs its intracellular trafficking (By similarity). Involved in ciliogenesis | lymphocyte-specific protein tyrosine kinase | 0.895 |