| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FXR2 | KRT20 | ENSP00000250113 | ENSP00000167588 | fragile X mental retardation, autosomal homolog 2; RNA-binding protein | keratin 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) | 0.635 |
| KRT15 | KRT20 | ENSP00000254043 | ENSP00000167588 | keratin 15 | keratin 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) | 0.494 |
| KRT20 | FXR2 | ENSP00000167588 | ENSP00000250113 | keratin 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) | fragile X mental retardation, autosomal homolog 2; RNA-binding protein | 0.635 |
| KRT20 | KRT15 | ENSP00000167588 | ENSP00000254043 | keratin 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) | keratin 15 | 0.494 |
| KRT20 | KRTAP19-5 | ENSP00000167588 | ENSP00000334985 | keratin 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) | keratin associated protein 19-5; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | 0.504 |
| KRT20 | MKI67 | ENSP00000167588 | ENSP00000357643 | keratin 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) | antigen identified by monoclonal antibody Ki-67; Thought to be required for maintaining cell proliferation | 0.410 |
| KRT20 | MUC2 | ENSP00000167588 | ENSP00000415183 | keratin 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) | mucin 2, oligomeric mucus/gel-forming; Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer | 0.469 |
| KRT20 | NKX2-1 | ENSP00000167588 | ENSP00000346879 | keratin 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) | NK2 homeobox 1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis | 0.423 |
| KRT20 | SLC4A3 | ENSP00000167588 | ENSP00000273063 | keratin 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) | solute carrier family 4, anion exchanger, member 3; Plasma membrane anion exchange protein of wide distribution. Mediates at least a part of the Cl(-)/HCO3(-) exchange in cardiac myocytes. Both BAE3 and CAE3 forms transport Cl(-) | 0.411 |
| KRTAP19-5 | KRT20 | ENSP00000334985 | ENSP00000167588 | keratin associated protein 19-5; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins | keratin 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) | 0.504 |
| MKI67 | KRT20 | ENSP00000357643 | ENSP00000167588 | antigen identified by monoclonal antibody Ki-67; Thought to be required for maintaining cell proliferation | keratin 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) | 0.410 |
| MUC2 | KRT20 | ENSP00000415183 | ENSP00000167588 | mucin 2, oligomeric mucus/gel-forming; Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer | keratin 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) | 0.469 |
| NKX2-1 | KRT20 | ENSP00000346879 | ENSP00000167588 | NK2 homeobox 1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis | keratin 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) | 0.423 |
| NKX2-1 | SLC4A3 | ENSP00000346879 | ENSP00000273063 | NK2 homeobox 1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis | solute carrier family 4, anion exchanger, member 3; Plasma membrane anion exchange protein of wide distribution. Mediates at least a part of the Cl(-)/HCO3(-) exchange in cardiac myocytes. Both BAE3 and CAE3 forms transport Cl(-) | 0.570 |
| SLC4A3 | KRT20 | ENSP00000273063 | ENSP00000167588 | solute carrier family 4, anion exchanger, member 3; Plasma membrane anion exchange protein of wide distribution. Mediates at least a part of the Cl(-)/HCO3(-) exchange in cardiac myocytes. Both BAE3 and CAE3 forms transport Cl(-) | keratin 20; Plays a significant role in maintaining keratin filament organization in intestinal epithelia. When phosphorylated, plays a role in the secretion of mucin in the small intestine (By similarity) | 0.411 |
| SLC4A3 | NKX2-1 | ENSP00000273063 | ENSP00000346879 | solute carrier family 4, anion exchanger, member 3; Plasma membrane anion exchange protein of wide distribution. Mediates at least a part of the Cl(-)/HCO3(-) exchange in cardiac myocytes. Both BAE3 and CAE3 forms transport Cl(-) | NK2 homeobox 1; Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis | 0.570 |
Share
