node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADCY1 | CNR1 | ENSP00000297323 | ENSP00000358511 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | cannabinoid receptor 1 (brain) | 0.900 |
ADCY1 | DRD4 | ENSP00000297323 | ENSP00000176183 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | dopamine receptor D4 | 0.933 |
ADCY1 | FPR3 | ENSP00000297323 | ENSP00000341821 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | formyl peptide receptor 3; Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system | 0.900 |
ADCY1 | GNG2 | ENSP00000297323 | ENSP00000334448 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | guanine nucleotide binding protein (G protein), gamma 2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity) | 0.937 |
ADCY1 | GRM3 | ENSP00000297323 | ENSP00000355316 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | glutamate receptor, metabotropic 3; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity | 0.923 |
ADCY1 | OPRM1 | ENSP00000297323 | ENSP00000394624 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | opioid receptor, mu 1 | 0.900 |
ADCY1 | PDYN | ENSP00000297323 | ENSP00000217305 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | prodynorphin; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity) | 0.901 |
ADCY1 | POMC | ENSP00000297323 | ENSP00000264708 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol | 0.913 |
ADCY1 | RXFP3 | ENSP00000297323 | ENSP00000328708 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | relaxin/insulin-like family peptide receptor 3; Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation | 0.900 |
CNR1 | ADCY1 | ENSP00000358511 | ENSP00000297323 | cannabinoid receptor 1 (brain) | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | 0.900 |
CNR1 | DRD4 | ENSP00000358511 | ENSP00000176183 | cannabinoid receptor 1 (brain) | dopamine receptor D4 | 0.932 |
CNR1 | FPR3 | ENSP00000358511 | ENSP00000341821 | cannabinoid receptor 1 (brain) | formyl peptide receptor 3; Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system | 0.900 |
CNR1 | GNG2 | ENSP00000358511 | ENSP00000334448 | cannabinoid receptor 1 (brain) | guanine nucleotide binding protein (G protein), gamma 2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity) | 0.906 |
CNR1 | GRM3 | ENSP00000358511 | ENSP00000355316 | cannabinoid receptor 1 (brain) | glutamate receptor, metabotropic 3; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity | 0.927 |
CNR1 | OPRM1 | ENSP00000358511 | ENSP00000394624 | cannabinoid receptor 1 (brain) | opioid receptor, mu 1 | 0.948 |
CNR1 | PDYN | ENSP00000358511 | ENSP00000217305 | cannabinoid receptor 1 (brain) | prodynorphin; Leu-enkephalins compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress (By similarity) | 0.948 |
CNR1 | POMC | ENSP00000358511 | ENSP00000264708 | cannabinoid receptor 1 (brain) | proopiomelanocortin; ACTH stimulates the adrenal glands to release cortisol | 0.954 |
CNR1 | RXFP3 | ENSP00000358511 | ENSP00000328708 | cannabinoid receptor 1 (brain) | relaxin/insulin-like family peptide receptor 3; Receptor for RNL3/relaxin-3. Binding of the ligand inhibit cAMP accumulation | 0.900 |
CNR1 | SLC6A3 | ENSP00000358511 | ENSP00000270349 | cannabinoid receptor 1 (brain) | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals | 0.499 |
DRD4 | ADCY1 | ENSP00000176183 | ENSP00000297323 | dopamine receptor D4 | adenylate cyclase 1 (brain); This is a calmodulin-sensitive adenylyl cyclase. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning | 0.933 |