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STRINGSTRING
PIK3R4 PIK3R4 C9orf96 C9orf96 C4orf32 C4orf32 ALPK1 ALPK1 UMODL1 UMODL1 RPS6KB2 RPS6KB2 LARP7 LARP7 FAM78B FAM78B NEK5 NEK5
"ALPK1" - alpha-kinase 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALPK1alpha-kinase 1; Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation (1244 aa)    
Predicted Functional Partners:
C4orf32
chromosome 4 open reading frame 32 (132 aa)
            score_image   0.589
LARP7
La ribonucleoprotein domain family, member 7; Negative transcriptional regulator of polymerase II genes, acting by means of the 7SK RNP system. Within the 7SK RNP complex, the positive transcription elongation factor b (P-TEFb) is sequestered in an inactive form, preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation (582 aa)
            score_image   0.504
C9orf96
chromosome 9 open reading frame 96 (680 aa)
            score_image   0.503
PIK3R4
phosphoinositide-3-kinase, regulatory subunit 4; Regulatory subunit of the PI3K complex. May regulate membrane trafficking late in the endocytic pathway (1358 aa)
            score_image   0.477
RPS6KB2
ribosomal protein S6 kinase, 70kDa, polypeptide 2; Phosphorylates specifically ribosomal protein S6 (482 aa)
            score_image   0.420
FAM78B
family with sequence similarity 78, member B (261 aa)
            score_image   0.414
NEK5
NIMA-related kinase 5 (708 aa)
            score_image   0.412
UMODL1
uromodulin-like 1 (1446 aa)
            score_image   0.407
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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