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GNPAT GNPAT AGPS AGPS DPM1 DPM1 LUZP4 LUZP4 FAR2 FAR2 MID2 MID2 FAM49A FAM49A MCHR2 MCHR2
"FAR2" - fatty acyl CoA reductase 2 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
FAR2fatty acyl CoA reductase 2; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. The preferred substrates are C16, C18, C18-1 and C18-2 but low activity can be observed with C10-C14 substrates (515 aa)    
Predicted Functional Partners:
GNPAT
glyceronephosphate O-acyltransferase (680 aa)
  score_image       score_image score_image   0.930
AGPS
alkylglycerone phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids (By similarity) (658 aa)
          score_image score_image   0.913
MID2
midline 2 (735 aa)
            score_image   0.531
LUZP4
leucine zipper protein 4 (313 aa)
            score_image   0.473
MCHR2
melanin-concentrating hormone receptor 2; Receptor for melanin-concentrating hormone, coupled to G proteins that activate phosphoinositide hydrolysis (340 aa)
            score_image   0.456
FAM49A
family with sequence similarity 49, member A (323 aa)
            score_image   0.445
DPM1
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O- mannosylation of proteins (260 aa)
            score_image   0.406
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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