node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HSPB11 | IFT122 | ENSP00000194214 | ENSP00000296266 | heat shock protein family B (small), member 11 | intraflagellar transport 122 homolog (Chlamydomonas); Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity) | 0.533 |
HSPB11 | IFT140 | ENSP00000194214 | ENSP00000406012 | heat shock protein family B (small), member 11 | intraflagellar transport 140 homolog (Chlamydomonas); Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance | 0.599 |
HSPB11 | IFT27 | ENSP00000194214 | ENSP00000393541 | heat shock protein family B (small), member 11 | intraflagellar transport 27 homolog (Chlamydomonas); Possesses GTPase activity (By similarity) | 0.997 |
HSPB11 | IFT46 | ENSP00000194214 | ENSP00000264020 | heat shock protein family B (small), member 11 | intraflagellar transport 46 homolog (Chlamydomonas); Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity) | 0.555 |
HSPB11 | IFT52 | ENSP00000194214 | ENSP00000362121 | heat shock protein family B (small), member 11 | intraflagellar transport 52 homolog (Chlamydomonas) | 0.657 |
HSPB11 | IFT88 | ENSP00000194214 | ENSP00000323580 | heat shock protein family B (small), member 11 | intraflagellar transport 88 homolog (Chlamydomonas); Involved in primary cilium biogenesis (By similarity) | 0.646 |
HSPB11 | SEC23IP | ENSP00000194214 | ENSP00000358071 | heat shock protein family B (small), member 11 | SEC23 interacting protein; Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P) | 0.607 |
HSPB11 | TTC21B | ENSP00000194214 | ENSP00000243344 | heat shock protein family B (small), member 11 | tetratricopeptide repeat domain 21B | 0.572 |
HSPB11 | TTC30B | ENSP00000194214 | ENSP00000386181 | heat shock protein family B (small), member 11 | tetratricopeptide repeat domain 30B; Required for polyglutamylation of axonemal tubulin (By similarity). Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip (By similarity) | 0.537 |
HSPB11 | WDR19 | ENSP00000194214 | ENSP00000382717 | heat shock protein family B (small), member 11 | WD repeat domain 19; Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Involved in cilia function and/or assembly (By similarity) | 0.538 |
IFT122 | HSPB11 | ENSP00000296266 | ENSP00000194214 | intraflagellar transport 122 homolog (Chlamydomonas); Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity) | heat shock protein family B (small), member 11 | 0.533 |
IFT122 | IFT140 | ENSP00000296266 | ENSP00000406012 | intraflagellar transport 122 homolog (Chlamydomonas); Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity) | intraflagellar transport 140 homolog (Chlamydomonas); Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance | 0.975 |
IFT122 | IFT27 | ENSP00000296266 | ENSP00000393541 | intraflagellar transport 122 homolog (Chlamydomonas); Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity) | intraflagellar transport 27 homolog (Chlamydomonas); Possesses GTPase activity (By similarity) | 0.812 |
IFT122 | IFT46 | ENSP00000296266 | ENSP00000264020 | intraflagellar transport 122 homolog (Chlamydomonas); Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity) | intraflagellar transport 46 homolog (Chlamydomonas); Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity) | 0.625 |
IFT122 | IFT52 | ENSP00000296266 | ENSP00000362121 | intraflagellar transport 122 homolog (Chlamydomonas); Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity) | intraflagellar transport 52 homolog (Chlamydomonas) | 0.850 |
IFT122 | IFT88 | ENSP00000296266 | ENSP00000323580 | intraflagellar transport 122 homolog (Chlamydomonas); Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity) | intraflagellar transport 88 homolog (Chlamydomonas); Involved in primary cilium biogenesis (By similarity) | 0.854 |
IFT122 | TTC21B | ENSP00000296266 | ENSP00000243344 | intraflagellar transport 122 homolog (Chlamydomonas); Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity) | tetratricopeptide repeat domain 21B | 0.954 |
IFT122 | WDR19 | ENSP00000296266 | ENSP00000382717 | intraflagellar transport 122 homolog (Chlamydomonas); Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity) | WD repeat domain 19; Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Involved in cilia function and/or assembly (By similarity) | 0.927 |
IFT140 | HSPB11 | ENSP00000406012 | ENSP00000194214 | intraflagellar transport 140 homolog (Chlamydomonas); Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance | heat shock protein family B (small), member 11 | 0.599 |
IFT140 | IFT122 | ENSP00000406012 | ENSP00000296266 | intraflagellar transport 140 homolog (Chlamydomonas); Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance | intraflagellar transport 122 homolog (Chlamydomonas); Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity) | 0.975 |