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STRINGSTRING
TTC30B TTC30B IFT46 IFT46 IFT52 IFT52 IFT140 IFT140 IFT27 IFT27 HSPB11 HSPB11 IFT88 IFT88 SEC23IP SEC23IP TTC21B TTC21B WDR19 WDR19 IFT122 IFT122
"HSPB11" - heat shock protein family B in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HSPB11heat shock protein family B (small), member 11 (144 aa)    
Predicted Functional Partners:
IFT27
intraflagellar transport 27 homolog (Chlamydomonas); Possesses GTPase activity (By similarity) (186 aa)
        score_image score_image score_image   0.997
IFT52
intraflagellar transport 52 homolog (Chlamydomonas) (437 aa)
          score_image score_image   0.657
IFT88
intraflagellar transport 88 homolog (Chlamydomonas); Involved in primary cilium biogenesis (By similarity) (833 aa)
        score_image score_image score_image   0.646
SEC23IP
SEC23 interacting protein; Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P) (1000 aa)
        score_image   score_image   0.607
IFT140
intraflagellar transport 140 homolog (Chlamydomonas); Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance (1462 aa)
          score_image score_image   0.599
TTC21B
tetratricopeptide repeat domain 21B (1316 aa)
          score_image score_image   0.572
IFT46
intraflagellar transport 46 homolog (Chlamydomonas); Forms part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. May play a role in chondrocyte maturation and skeletogenesis (By similarity) (355 aa)
            score_image   0.555
WDR19
WD repeat domain 19; Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Involved in cilia function and/or assembly (By similarity) (1342 aa)
          score_image score_image   0.538
TTC30B
tetratricopeptide repeat domain 30B; Required for polyglutamylation of axonemal tubulin (By similarity). Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip (By similarity) (665 aa)
            score_image   0.537
IFT122
intraflagellar transport 122 homolog (Chlamydomonas); Required for cilia formation during neuronal patterning. Acts as a negative regulator of Shh signaling. Required to recruit TULP3 to primary cilia (By similarity) (1292 aa)
          score_image score_image   0.533
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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